三种手术科室病人乙型肝炎病毒感染情况

Hepatitis B virus infection in three types of surgical department patients

目的调查三种手术科室病人乙型肝炎病毒(HBV)感染情况,为开展乙肝防治工作提供参考。方法回顾2006～2012年就诊于吉林大学第一医院的分娩人群及腹股沟疝、阑尾炎病人的乙肝标志物检查结果及人口学资料。χ2检验乙肝表面抗原(HBsAg)阳性率是否存在性别或年龄差异。结果总体HBsAg阳性率为4.14%,分娩组、腹股沟疝组、阑尾炎组HBsAg阳性率分别为4.42%、3.14%和3.82%。男、女HBsAg阳性率无统计学差异(4.37%vs 4.09%,P=0.742);高年龄组HBsAg阳性率显著高于低年龄组(5.45%vs 3.06%,P<0.01)。结论乙肝疫苗普及使年轻人群HBV感染率下降,分娩人群HBV感染率仍较高,应加强乙肝母婴传播的阻断,以防止新的HBV感染。

Objective To investigate the Hepatitis B virus （HBV） infection in three types of surgical department patients,learning about the present HBV infection status, providing references for the development of the HBV prevention and control work. Methods A survey of HBsAg prevalence among all pregnant women and patients with inguinal hernia or appendicitis hospitalized in the First hospital of Jilin University from 2006 to 2012 was conducted. Data on demographic variables and HBsAg test results were collected. Chi-square test was used to compare the HBsAg prevalence between different age or gender groups. Results The overall prevalence of HBsAg positivity was 4. 14%. The prevalence in pregnant women, appendicitis and inguinal hernia was 4.42% , 3.14% and 3.82% , respectively. No significant difference between male and female was observed（ P = 0. 742）. The HBsAg prevalence of old group was higher than that of young group after stratified according to median age （ P = 4. 21 × 10 -4 ）. Conclusions With the Hepatitis B vaccination, the HBsAg prevalence of young people has declined. But the prevalence of pregnant women is 4. 42% , the prevention of mother-to-child transmission should be strengthened to prevent new HBV infection.