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糖尿病视网膜病变患者血清中血管内皮生长因子和色素上皮衍生因子水平的变化 被引量:5

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摘要 糖尿病视网膜病变(DR)基本病理改变是血视网膜屏障破坏,新生血管形成。血管内皮生长因子(VEGF)是促进血管生成的重要因子之一,通过促进内皮细胞增生,改变细胞外基质及增加血管通透性促进血管新生。色素上皮衍生因子(PEDF)可以通过抑制炎症以及氧化应激反应,促进内皮细胞凋亡等抑制新生血管形成。为了解VEGF与PEDF水平在DR发生发展过程中的变化,我们对一组糖尿病患者和DR患者的血清VEGF与PEDF进行了测定,现将结果报道如下。
出处 《中华眼底病杂志》 CAS CSCD 北大核心 2013年第1期80-82,共3页 Chinese Journal of Ocular Fundus Diseases
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参考文献17

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