恩施绿茶茶多糖对糖尿病模型大鼠血糖的影响

Effects of Enshi green tea tea polysaccharide on serum glucose in experimental diabetic rats

目的:研究恩施绿茶茶多糖对糖尿病模型大鼠血糖的影响。方法:用四氧嘧啶(alloxan)建立糖尿病模型大鼠,行恩施绿茶茶多糖灌胃4周,观察糖尿病大鼠血糖(FBG)、胰岛素(INS)、肝葡萄糖激酶(GK)、血清中丙二醛(MDA)、超氧化物歧化酶(SOD)和谷胱甘肽过氧化物酶(GSH-Px)以及脾脏、胸腺系数的变化。结果:恩施绿茶茶多糖能明显降低糖尿病大鼠的FBG,增强GK、SOD和GSH-Px的活性,减少MDA的含量,升高脾脏、胸腺系数。结论:恩施绿茶茶多糖具有降血糖,抗氧化和增强机体免疫功能的作用。

Objective： To study the effects of Enshi green tea tea polysaccharide on serum glucose in experimental diabetic rats.Methods： Diabetic rats model were established by alloxan,Enshi green tea tea polysaccharide was poured into rats’ stomach for four weeks,then the changes of the level about fasting blood glucose（FBG）,glucokinase（GK）,insulin（INS）,malondialdehyde（MDA）,superoxide dismutase（SOD）,glutathione peroxidase（GSH-Px）,spleen index and thymus index were observed.Results： Enshi green tea tea polysaccharide could reduce the level of FBG in diabetic rats,and increase the activity of KG,SOD and GSH-Px,moreover,it could reduce the level of MDA and increase the spleen index and thymus index.Conclusion： Enshi green tea tea polysaccharide has remarkable effect on playing down the blood suger,and can increase the antioxygenic activity and immunity.