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上皮间质转化与肿瘤耐药 被引量:5

Epithelial-mesenchymal Transition and Tumor Drug Resistance
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摘要 肿瘤药物治疗过程中常常要面临肿瘤细胞耐药的问题。上皮间质转化(epithelial-mesenchymaltransition,EMT)在肿瘤耐药方面的作用为解决该问题提供了可能。该文围绕EMT基本特征、EMT与肿瘤耐药的关系、EMT在肿瘤耐药过程中机制的研究进展进行详细综述。 [ Abstract ] Resistance to antineoplastic drugs is a common problem in cancer treatments. Epithelial-mesenchymal transition (EMT), which plays an important role in the process of drug resistance, may provide opportunity to solve this prob- lem. "Ihis article reviews the characteristics of EMT, relationship between EMT and drug resistance, mechanism of EMT in tumor drug resistance in details.
出处 《中国肺癌杂志》 CAS 北大核心 2013年第1期54-57,共4页 Chinese Journal of Lung Cancer
基金 国家自然科学基金重点项目(No.30430300) 国家自然科学基金(No.30973384) 国家"863"重大项目(No.2006AAOZA401) 国家"973"重大项目(No.2010CB529405) 天津医科大学科学基金(No.2012kyq16) 吴阶平医学基金会临床科研专项资助基金(No.320.6750.12248)资助~~
关键词 上皮间质转化 肿瘤 耐药 Epithelial-mesenchymal transition Tumor Drug resistance
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