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抑郁症引起急性早幼粒细胞白血病及文献复习

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摘要 急性早幼粒细胞白血病(acute promyelocytic leukemia,APL)是急性髓细胞白血病中较特殊的一个类型,90%以上的APL患者有特异性的染色体易位t(15;17)(q22;q21),95%以上的的患者可检测到早幼粒细胞白血病(promyelocyticleukemia,PML)/维甲酸受体(retinocacidreceptor,RAR)融合基因。由于患者易合并弥散性血管内凝血(disseminated intravascular coagulation,DIC)和纤维蛋白溶解。20世纪80年代之前绝大多数患者在达到完全缓解(complete remission,CR)前死于出血;
出处 《国际输血及血液学杂志》 CAS 2013年第1期11-12,共2页 International Journal of Blood Transfusion and Hematology
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参考文献12

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