期刊文献+

体外光化学疗法在治疗移植物抗宿主病中的应用研究

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摘要 移植物抗宿主病(GVHD)是异基因造血干细胞移植(alloHSCT)后一种常见的并发症,研究显示体外光化学疗法(ECP)现已成为一种治疗GVHD的有效手段,其治疗作用主要通过诱导细胞凋亡及免疫耐受、影响树突状细胞而实现,具体机制尚不明确;但ECP治疗成人及儿童急、慢性GVHD效果均明显,不增加感染风险,不影响移植物抗白血病效应,副作用小。现就ECP治疗GVHD的研究进展作一综述。
出处 《国际输血及血液学杂志》 CAS 2013年第1期64-67,共4页 International Journal of Blood Transfusion and Hematology
基金 江苏省临床医学研究中心项目(BL2012005),江苏省卫生厅面上项目(H201212),苏州市科技发展计划项目(SS0718),江苏省临床医学中心血液病学开放课题(KF200943)
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  • 1McKenna KE,Whittaker S,Rhodes LE. British Photodermatology Group & UK Skin Lymphoma Group.Evidence-based practice of photopheresis 1987-2001:a report of a workshop of the British Photodermatology Group and UK Skin Lymphoma Group[J].British Journal of Dermatology,2006,(01):7-20.
  • 2Heshmati F,Andreu G. Extracorporeal photochemotherapy:a historical perspective[J].Tranfus Apher Sci,2003,(01):25-34.
  • 3Duvic M,Chiao N,Talpur R. Extracorporeal photopheresis for the treatment of cutaneous T-cell lymphoma[J].Journal of Cutaneous Medicine and Surgery,2003,(4 Suppl):3-7.
  • 4Greinix HT,Socié G,Bacigalupo A. Assessing the potential role of photopheresis in hematopoietic stem cell transplant[J].Bone Marrow Transplantation,2006,(04):265-273.doi:10.1038/sj.bmt.1705440.
  • 5Edelson RL. Transimmunization:the science catches up to the clinical success[J].Transfusion and Apheresis Science,2002,(03):177-180.
  • 6Messina C,Locatelli F,Lanino E. Extracorporeal photochemotherapy for paediatric patients with graft-versus-host disease after haematopoietic stem cell transplantation[J].British Journal of Haematology,2003,(01):118-127.doi:10.1046/j.1365-2141.2003.04401.x.
  • 7Peritt D. Potential mechanisms of photopheresis in hematopoietic stem cell transplantation[J].Biology of Blood and Marrow Transplantation,2006,(1Suppl 2):7-12.
  • 8González-Vicent M,Ramírez M,Pérez A. Extracorporeal.photochemotherapy for steroid-refractory graft-versus-host disease in low-weight pediatric patients.Immunomodulatory effects and clinical outcome[J].Haematologica,2008,(08):1278-1280.
  • 9Kanold J,Merlin E,Halle P. Photopheresis in pediatric graft-versus host disease after allogeneic marrow transplantation:clinical practice guidelines based on field experience and review of the literature[J].Transfusion,2007,(12):2276-2289.
  • 10Perotti C,Del Fante C,Tinelli C. Extracorporeal photochemotherapy in graft-versus-host disease:a longitudinal study on factors influencing the response and survival in pediatric patients[J].Transfusion,2010,(06):1359-1369.

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