福建省大城市点居民维生素A营养状况调查

Nutrition status of vitamin A among residents in major cities of Fujian province

目的了解福建省大城市点居民血清维生素A(VA)营养状况,为进一步实施营养干预提供科学依据。方法从2010年中国居民营养与健康状况监测的福州、厦门2大城市监测点的血样中,按VA测定采样要求随机抽取总计392人,采用高效液相色谱紫外检测法及内标定量法测定血清视黄醇水平并评价人群VA营养状况。结果福建省大城市点居民VA平均水平为(0.458±0.174)mg/L,不同性别、年龄VA平均水平差异均有统计学意义(P<0.01),福州、厦门2大城市点VA水平差异无统计学意义(P>0.05);调查的392名居民中,VA缺乏者占3.3%,边缘性VA缺乏者占14.3%,VA充足者占82.7%;不同年龄VA营养状况差异有统计学意义(χ2=23.40,P=0.001),VA缺乏和边缘性VA缺乏所占比例均随着年龄上升呈下降趋势,不同性别、城市点VA营养状况差异均无统计学意义(P>0.05)。结论福州、厦门2大城市点居民维生素A营养状况不容乐观,随年龄的增长,VA缺乏和边缘性VA缺乏所占比例随之下降。

Objective To evaluate the nutrition status of vitamin A among the residents in major cities of Fujian province. Methods Blood samples were collected from the residents in Fuzhou and Xiamen city, which were the cities sampled for National Nutrition and Health Survey 2010. A total of 392 subjects were randomly selected according to sampiing requirements for vitamin A determination. The serum retinol levels were determined with high performance liquid chromatography（HPLC） coupled with ultraviolate detector and quantified with internal standard method. Results There was gender difference（ F = 7. 267 ,P = 0. 005 ） in serum vitamin A concentration but there was no significant difference in vitamin A concentration between the residents of Fuzhou and Xiamen （ F = 0. 004, P = 0. 949 ）. The vitamin A deficiency among the residents was 3.3 %, and the marginal vitamin A deficiency was 14. 3%. The prevalences of vitamin A deficiency and marginal vitamin A deficiency were decreased with age（X^2 = 18.90, P 〈 0. 001 ）. There were no significant differences in the prevalence of vitamin A deficiency between the residents of different gender（X^2 = 1.99, P = 0. 37 ） and cities （X2 = 2. 15,P=0. 34）. Conclusion The vitamin A nutrition status in the residents of major cities in Fujian province is not optimistic and attention should be paid to the problem in the residents. The vitamin A deficiency and marginal vitamin A deficiency decreased with the increment of age in the residents.