血府逐瘀胶囊预防结核性渗出性胸膜炎引发胸膜肥厚及粘连的临床观察

Clinical Observation on the Prevention of Pleural Thickening and Adhesion Induced by Tuberculosis Exudative Pleurisywith Xuefuzhuyu Capsules

目的:探讨血府逐瘀胶囊预防结核性渗出性胸膜炎引发胸膜肥厚、粘连的临床观察。方法:选取2010年1月～2012年6月于本院进行治疗的56例结核性渗出性胸膜炎患者为研究对象,将其随机分为对照组(常规治疗组)和观察组(常规治疗加血府逐瘀胶囊组),每组各28例,观察2组患者的胸膜肥厚和粘连发生率并对治疗前后胸腔积液蛋白定量、纤维蛋白原、壁层胸膜厚度、肺功能指标进行检测及比较。结果:观察组的胸膜肥厚和粘连发生率低于对照组,治疗后1周、2周的胸腔积液蛋白定量、纤维蛋白原、壁层胸膜厚度、肺功能指标均优于对照组,有显著性差异(P<0.05)。结论:血府逐瘀胶囊预防结核性渗出性胸膜炎引发胸膜肥厚、粘连的临床价值较高。

Objective: To study the clinical effectiveness of Xuefuzhuyu capsules on the prevention of pleural thickening and adhesions induced by tuberculous exudative pleurisy.Methods: 56 tuberculous exudative pleurisy patients visiting our hospital from January 2010 to June 2012 were selected and randomly divided into a control group(conventional treatment group) and observation group(conventional treatment plus Xuefuzhuyu capsule group),28 patients per group.The pleural thickening and adhesion incidence of the patients of the two groups were observed and their pleural effusion protein,fibrinogen,parietal pleura thickness and lung function indicators were detected and compared before and after the treatment.Results: The pleural thickening and adhesion incidence of the observation group was less than that of the control group.The pleural effusion protein,fibrinogen,parietal pleura thickness and lung function indicators after 1-week and 2-week treatment were better than that of the control group,showing significant difference(P<0.05).Conclusion: Xuefuzhuyu capsules have a higher clinical value for preventing the pleural thickening and adhesions induced by the tuberculosis exudative pleurisy.