进一步优化胃癌综合治疗的方案与措施

Further improving the result of multi-modality treatment for gastric cancer by optimizing scheme and measures

全球胃癌发病率呈逐渐下降趋势，但我国人口众多，每年新发胃癌人数仍极庞大。国内多家诊疗中心已建立了胃癌多学科诊疗团队，但在外科手术、化疗、放疗乃至生物靶向治疗等具体策略方面，仍有进一步优化的空间。目前的研究热点包括：合理应用各种技术做精确的术前分期、局部进展期胃癌的围手术期化疗、微创外科技术在各期胃癌中的应用价值、临床研究与基础科研的合理转化以及胃癌的个体化治疗等。中西方胃癌的生物学行为及各类分子事件存在差异，期待有更多源自东方的临床研究证据，充实我国胃痛治疗临床实践。

The incidence of gastric cancer has declined worldwide in the past decades. However, due to the large number of population in mainland of China, the absolute number of newly-diagnosed patients in this developing country is still very high. Most of the major clinical centers have established multi-disciplinary＇ team, but the strategy in treating this lifehreatening disease still needs to be optimized, including the precise preoperative staging by various techniques, perioperative chemotherapy for locally advanced diseases, role ofminimally invasive surgical approaches in treating patients with different stages, translational research to fill the gap between clinical trials and basic research, as well as the individualized treatment for gastric cancer. We believe that the biological behaviors and molecular events of gastric cancer in eastern countries are different from that of Western countries, so the clinical evidences derived from Eastern countries need to be strengthened to enrich the unmet demands in the clinical practice in China.