计算机辅助精液检查及精子形态分析在不孕症诊疗中的运用

The application of computer-aided semen analysis and sperm morphology in diagnosis and treatment of infertility

目的对不育男性患者进行计算机辅助精液检查及精子形态分析,探讨广东省湛江地区男性不育的原因。方法随机选取130例男性不育患者及90名已育男性精液标本作对照组,进行计算机辅助精液检查及精子形态分析。结果观察组与对照组比较,精液量、精子浓度,前向运动精子差异均有统计学意义(P<0.01)。直线速度、平均速度、线性指数、直性指数、振动指数、头部侧向平均振幅、鞭打频率差异均有统计学意义(P<0.01)。2组正常形态精子百分率差异有统计学意义(P<0.01)。结论计算机辅助精液检查及精子形态分析是分析判断男性生育力的重要检测手段,为不孕症的诊疗提供有力依据。

Objective To investigate the reason of male infertility, computer-aided semen analysis and sperm morphology of infertile men in Zhanjiang were analyzed. Methods The parameters of semen samples from 130 infertile and 90 fertile men were measured by using computer-aided semen analysis （CASA） and sperm morphology analysis. Results There was significant difference between infertile and fertile group in the main parameters such as semen volume, sperm density, rate of sperm forward movement sperm （P〈0.01）. Sperm movement parameters such as VSL, VAP, LIN, STR, WOB, ALH, BCF were differently higher than that in the control group （P〈0.01）. The significant difference of normal sperm morphology rate existed between infertile and fertile group （P〈0.01）. Conclusion CASA and sperm morphology should be used as an important method for male infertility diagnose, and it could provide powerful evidence for infertility diagnosis and treatment.