桃红三虫汤治疗急性脑梗死患者疗效分析

Clinical Research on Taohong Sanchong Decoction for Treatment of Acute Cerebral Infarction

目的:观察桃红三虫汤对急性脑梗死(风痰瘀阻型)的疗效及对血脂、血液黏度的影响。方法:86例急性脑梗死(风痰瘀阻型)患者按随机数字表分为观察组44例、对照组42例,两组均采用西医常规治疗,对照组服用血滞通胶囊,治疗组服用自拟桃红三虫汤。治疗8周后观察临床疗效、血脂、血液黏度的变化。结果:总有效率观察组为90.9%,对照组为83.3%,两组有显著差异(P<0.05),观察组优于对照组;与治疗前比较,治疗后两组血脂[甘油三酯(TG)、胆固醇(TC)、低密度脂蛋白(LDL-C)]、血黏度均明显降低(P<0.05或P<0.01);治疗后观察组血TC,TG,全血黏度、血球压积、纤维蛋白原明显低于对照组(P<0.05或P<0.01)。结论:桃红三虫汤可能是通过调节血脂、血液黏度水平,而对急性脑梗死(风痰瘀阻型)患者产生较好的疗效。

Objective： To investigate the clinical effect of Taohong Sanchong decoction （TSD） on acute cerebral infarction. Method ： Eighty-six cases of acute cerebral infarction were divided into observe group 44 cases and control group 42 cases. Two groups were treated by routine western medicines. The control group was also treated by Xuezhitong capsules, while the observe group was also treated by TSD. The clinical efficacy and changes in blood lipids and blood viscosity were investigated, after 8 weeks treatment for the two groups. Result： The total effective rates in the treatment group was 90.9% and the control group was 83.3% respectively with a significant difference （P 〈 0.05 ）. There were significant differences in the levels of total cholesterol （ TC）, trilyceride （TG）, low density lipoprotein （LDL-C） and blood viscosity between before and after treatment in the two groups （P 〈0.05 or P 〈0.01）. After treatment, TC, TG, blood viscosity, HCT and fibrinogen in the treatment group were significantly lower than those in the control group （P 〈 O. 05, P 〈 0.01）. Conclusion ： TSD may adjust the level of blood lipids and blood viscosity, increase the clinical efficacy for treatment of acute cerebral infarction.