盆炎净颗粒结合康妇消炎栓治疗盆腔炎性疾病后遗症

Clinical Research on Penyanjing Granule Combined with Kangfu Xiaoyan Suppositories for Treatment of Sequela after Pelvic Inflammatory Disease

目的:观察盆炎净颗粒结合康妇消炎栓治疗盆腔炎性疾病后遗症(SPID)的临床疗效及对血液流变学的影响。方法:147例SPID患者随机分为治疗组74例和对照组73例。治疗组盆炎净颗粒口服,10 g/次,3次/d;康妇消炎栓外用,1粒/次,1次/d,疗程1个月经周期。对照组左氧氟沙星口服,0.2/次,2次/d;甲硝唑片口服,0.4 g/次,2次/d,疗程14 d。观察两组临床症状与体征,并检测血液流变学指标。结果:治疗后治疗组症状、体征积分为(4.52±2.14)分,低于对照组的(10.57±3.75)分(P<0.01);治疗组血液流变各项指标改善也优于对照组(P<0.01);治疗组总有效率90.54%,优于对照组的78.08%(P<0.05)。结论:盆炎净颗粒结合康妇消炎栓是治疗盆腔炎性疾病后遗症较好的治疗方案。

Objective： To observe Penyanjing granule （PG） combined with Kangfu Xiaoyan suppositories （KXS） for treatment of sequela after pelvic inflammatory disease （SPID） and effect on hemorheological parameters. Method： One hundred and forty-seven cases of SPID were randomly divided into treatment group and control group, 74 cases and 73 cases respectively. The treatment group was given PG orally, 10 g tid; combined with KXS for external use, 1 application daily. The period of treatment was lasted one menstrual cycle. The control group was given levofloxacin orally, 0.2 g, bid and metronidazole tablets, 0.4 g, bid. The course was 14 days.The clinical symptoms, signs and hemorheological parameters were observed for both groups. Result： After treatment, the scores of symptoms, signs and symptoms were （4.52 ＋2.14） in treatment group, lower than that of （ 10.57 _＋ 3.75 ） in the control group （P 〈 0.01 ）. The improvement of hemorheological parameters in treatment was also superior to those in the control group （P 〈 0. 01 ）. The total curative rate in treatment group was 90.54% , better than 78.08% in control group （P 〈 0.05）. Conclusion： PG combined with KXS is an effective treatment for treating SPID. It is worth for clinical use.