摘要
近年来诸多研究者就肺高血压发病机制,病理进程及药物治疗靶点等方面进行了深入研究。2011年欧洲三个独立的实验室先后报道在特发性肺动脉高压(idiopathic pulmonary anerial hypertension,IPAH)人群中出现铁缺乏、铁代谢紊乱,其发病机制尚不明确;另外有研究发现,
出处
《中华心血管病杂志》
CAS
CSCD
北大核心
2013年第1期76-78,共3页
Chinese Journal of Cardiology
基金
国家“重大新药创制”科技重大专项(2012zx09303014-001)
重大基础研究前期研究专项(2011CB512001)
湖南省国际合作科技计划重点项目(2010WK2006)
国家自然科学基金(81200035)
同被引文献18
-
1Vincent G DeMarco,Adam T Whaley-Connell,James R Sowers,Javad Habibi,Kevin C Dellsperger.Contribution of oxidative stress to pulmonary arterial hypertension[J].World Journal of Cardiology,2010,2(10):316-324. 被引量:21
-
2McLaughlin VV, Archer SL, Badesch DB, et al. ACCF/AHA 2009 expert consensus document on pulmonary hypertension a re- port of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Associa- tion developed in collaboration with the American College of Chest Physicians ; American Thoracic Society, Inc ; and the Pul- monary Hypertension Association [ J ]. J Am Coll Cardiol, 2009, 53(17) : 1573-1619.
-
3Simes PA, Tendera M, Vardas P, et al. Guidelines for the diag- nosis and treatment of pulmonary hypertension[J]. Eur Heart J, 2009, 30: 2493-2537.
-
4Soon E, Treacy CM, Toshner MR, et al. Unexplained iron defi- ciency in idiopathic and heritable pulmonary arterial hypertension [J]. Thorax, 2011,66(4) : 326-332.
-
5Ruiter G, Lankhorst S, Boonstra A, et al. Iron deficiency is com- mon in idiopathic pulmonary arterial hypertension[ J]. Eur Respir J, 2011, 37(6) : 1386-1391.
-
6Rhodes CJ, Howard KS, Busbridge M, et al. Ilron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension : clin- ical prevalence, outcomes, and mechanistic insights [ J ]. J Am Coll Cardiol, 2011, 58(3): 300-309.
-
7van Empel VP, Lee J, Williams TJ, et al. Iron deficiency in pa- tients with idiopathic pulmonary arterial hypertension [ J ]. Heart Lung Circ, 2014, 23(3): 287-292.
-
8Smith TG, Balanos GM, Croft QP, et al. The increase in pulmo- nary arterial pressure caused by hypoxia depends on iron status [ J]. J Physiol, 2008, 586(Pt 24): 5999-6005.
-
9Smith TG, Talbot NP, Privat C, et al. Effects of iron supplemen- tation and depletion on hypoxic pulmonary hypertension: two ran- domized controlled trials [ J ]. JAMA, 2009, 302 ( 13 ) : 1444- 1450.
-
10Finch CA, Miller LR, lnamdar AR, et al. Iron deficiency in the rat. Physiological and biochemical studies of muscle dysfunction [J]. J Clin Invest, 1976, 58(2) : 447-453.
二级引证文献4
-
1田香珠,刘学源.细胞内铁沉积对PC12细胞凋亡及表达3-磷酸甘油醛脱氢酶的影响[J].医学研究生学报,2016,29(8):818-821.
-
2马庆东,刘运胜.低氧条件下的铁代谢研究进展[J].西北国防医学杂志,2017,38(1):65-68. 被引量:2
-
3樊青曼,刘俊峰,陈玉芝,王连芳,刘伟娟,刘士霞.西地那非治疗新生儿肺动脉高压及其对循环内皮祖细胞及肿瘤坏死因子-α的影响[J].贵州医科大学学报,2018,43(6):686-689. 被引量:2
-
4宋丽丽.铁稳态对肺动脉高压影响的研究进展[J].河北医药,2022,44(15):2364-2368. 被引量:1
-
1何戎华,胡新艳,杨鹏云.糖尿病铁代谢异常及其临床意义[J].南京医学院学报,1993,13(2):110-112. 被引量:1
-
2谢宗林,陶康,赵先英,刘毅敏.铁过载与糖尿病的关系研究进展[J].国际检验医学杂志,2014,35(11):1463-1465. 被引量:5
-
3沈建箴,吕联煌.SLE患者贫血与铁代谢异常[J].中华皮肤科杂志,1991,24(5):332-333. 被引量:5
-
4陈仁荃,林建辉.乙型肝炎肝损伤中铁代谢异常的临床意义探讨[J].中西医结合肝病杂志,2001,11(S1):51-52.
-
5静脉蔗糖铁 对慢性心力衰竭合并铁缺乏患者运动耐量的作用[J].中国处方药,2008(2):56-56.
-
6奚群英,柳志红.铁代谢与心血管疾病[J].心血管病学进展,2014,35(2):196-200. 被引量:1
-
7林韬.特发性肺含铁血黄素沉着症误诊3例报告[J].中国乡村医药,2005,12(8):32-32.
-
8闫鲲,师海蛟,刘新军.血清铁蛋白水平与2型糖尿病及其并发症相关性研究[J].世界临床药物,2014,35(7):431-434. 被引量:4
-
9病毒性肝炎:总论[J].传染病网络动态,2007(11):73-74.
-
10冯烨,李成江,张楚.非酒精性脂肪肝病与铁代谢异常的相关性分析[J].临床内科杂志,2011,28(6):409-411. 被引量:12