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中性粒细胞CD64在类风湿关节炎合并感染者中的表达及意义 被引量：8

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摘要 分化群抗原64（cluster of differentiation antigen，CD64）具有识别免疫球蛋白、高亲和IgG单体、介导体液免疫和细胞免疫及早期诊断感染性疾病IgGFc片段受体1（FcγR I）的功能，可通过抗体依赖性细胞毒和细胞吞噬及免疫复合物清除作用清除病原微生物[1]。
作者 李德红 李勇 居军 鲁彦
机构地区 甘肃省人民医院检验中心 解放军第一医院检验科
出处 《中华检验医学杂志》 CAS CSCD 北大核心 2013年第1期77-79,共3页 Chinese Journal of Laboratory Medicine
关键词 中性粒细胞CD64 类风湿关节炎 感染者 免疫球蛋白 感染性疾病 病原微生物 免疫复合物 抗体依赖性
分类号 R593.22 [医药卫生—内科学]
  • 相关文献

参考文献14

  • 1Hoffmann JJ. Neutrophil CD64:a diagnostic marker for infection and sepsis[J].Clinical Chemistry and Laboratory Medicine,2009.903-916.
  • 2Matsui T,Ohsumi K,Ozawa N. CD64 on neutrophils is a sensitive and specific marker for detection of infection in patients with rheumatoid arthritis[J].Journal of Rheumatology,2006.24-16-2424.
  • 3杨旭燕,林进,厉有名.系统性红斑狼疮患者外周血中性粒细胞CD_(64)的表达[J].中华内科杂志,2003,42(12):854-856. 被引量：13
  • 4Tillinger W,Jilch R,Jilma B. Expression of the high-affinity IgG receptor FcRI (CD64) in patients with inflammatory bowel disease:a new biomarker for gastroenterologic diagnostics[J].American Journal of Gastroenterology,2009.102-109.
  • 5Migita K,Agematsu K,Yamazaki K. Expression of CD64 on polymorphonuclear neutrophils in patients with familial Mediterranean fever[J].Clinical and Experimental Immunology,2011.365-372.
  • 6Komiya A,Matsui T,Nogi S. Neutrophil CD64 is upregulated in patients with active adult-onset Still 's disease[J].Scandinavian Journal of Rheumatology,2012.156-158.
  • 7李广科,李宝全,巩路.类风湿关节炎患者血清人软骨糖蛋白-39的检测和意义[J].天津医科大学学报,2009,15(4):603-605. 被引量：3
  • 8Hussein OA,E1-Toukhy MA,El-Rahman HS. Neutrophil CD64 expression in inflammatory autoimmune diseases:its value in distinguishing infection from disease flare[J].Immunological Investigations,2010.699-712.
  • 9Allen E,Bakke AC,Purtzer MZ. Neutrophil CD64 expression:distinguishing acute inflammatory autoimmune disease from systemic infections[J].Annals of the Rheumatic Diseases,2002.522-525.
  • 10Goulding NJ,Knight SM,Godolphin JL. Increase in neutrophil Fc gamma receptor I expression following interferon gamma treatment in rheumatoid arthritis[J].Annals of the Rheumatic Diseases,1992.465-468.

二级参考文献13

  • 1简序,王金和,程佩兰.C反应蛋白的临床研究进展[J].国际检验医学杂志,2004,26(5):471-473. 被引量：137
  • 2沈敏,曾学军,唐福林.类风湿关节炎外周血单个核细胞和滑膜中人类软骨糖蛋白-39的研究[J].中华内科杂志,2004,43(12):928-931. 被引量：4
  • 3董怡.类风湿关节炎[M]//叶任高,陆再英.内科学.6版.北京:人民卫生出版社,2004:885-891.
  • 4Baeten D, Boots AM, Steenbakkers PG, et al. Human cartilage gp- 39+,CD16 + monocytes in peripheral blood and synovium: correlation with joint destruction in rheumatoid arthritis [J]. Arthritis Rheum, 2000,43 (6):1233.
  • 5Johansen JS ,Stohenberg M,Hansen M,et al . Serum YKL-40 concentrations in patients with rheumatoid arthritis : relation to disease activity [J]. Rheumatology (Oxford) ,1999,38(7):618.
  • 6Vos K, Steenbakkers P, Mihenburg AM, et al. Raised human cartilage glycoprotein-39 plasma levels in patients with rheumatoid arthritis and other inflammatory conditions [J]. Ann Rheum Dis, 2000,59 (7):544.
  • 7Harvey S, Weisman M, O'dell J, et al. Chondrex: new marker of joint disease [J].Clin Chem,1998,44(3):509.
  • 8Bukhari M, Hanison B, Lunt M, et al. Time to first occurrence of erosions in inflammatory polyarthritis: results from a prospective community-based study [J}. Arthritis Rheum, 2001,44 (6): 1248.
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  • 10Hakala BE ,White C ,Reeklies AD. Human cartilage gp-39 ,a major secretary product of articular chondroeytes and synovial cells, is a mammalian member of a ehitinase protein family [J]. J Biol Chem, 1993,268(34):25803.

共引文献21

同被引文献97

  • 1张蓉,陈超.CD64对新生儿败血症早期诊断的评估[J].复旦学报（医学版）,2006,33(1):53-55. 被引量：5
  • 2徐茜茜,陈灵芝,徐海滨,张宇,包曼华.CD64在新生儿感染诊断中的价值[J].临床儿科杂志,2006,24(3):185-187. 被引量：7
  • 3徐茜茜,陈灵芝,徐海滨,张宇,包曼华.CD64在早产儿细菌性感染中的应用价值[J].中国免疫学杂志,2007,23(2):161-163. 被引量：7
  • 4郝玲,杨恒伟,李艳芝,李彦敏,刘桂玲.新生儿败血症中性粒细胞CD64、CD11b的表达及临床意义[J].临床荟萃,2007,22(19):1382-1385. 被引量：5
  • 5Davis BH, Olsen SH, Ahmad E, et al. Neutrophil CD64 is an improved indicator of infection or sepsis in emergency depart- ment patients[J]. Arch Pathol Lab Med, 2006,130 (5) : 654 -661.
  • 6Dilli D, Oguz S, Dilmen U, et al. Predictive values of neu trophil CD64 expression compared with interleukin-6 and C- reactive protein in early diagnosis of neonatal sepsis[J]. J Clin Lab Anal,2010,24(6) :363-370.
  • 7Livaditi O, Kotanidou A, Psarra A, et al. Neutrophil CD64 expression and serum IL-8 : sensitive early markers of severity and outcome in sepsis[J]. Cytokine,2006,36(5/6) :283-290.
  • 8Song SH, Kirn HK, Park MH, et al. Neutrophil CD64 ex- pression is associated with severity and prognosis of dissemi- nated intravascular coagulation [J]. Thromb Res, 2008, 121 (4) :499-507.
  • 9Hoffmann JJ. Neutrophil CD64 : a diagnostic marker for infection and sepsis[ J]. Clin Chem Lab Med, 2009, 47 ( 8 ) :903 - 916.
  • 10Wagner C, Deppisch R, Denefleh B, et al. Expression patterns of the lipopolysaccharide receptor CDI4, and the FCgamma re- ceptors CD16 and CD64 on polymorphonuclear neutrophils: data from patients with severe bacterial infections and lipopolysaccha- r/de-exposed cells [ J]. Shock, 2003, 19( 1 ) : 5 - 12.

引证文献8

二级引证文献41

中华检验医学杂志
2013年 第1期

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