正常婴幼儿及成人蜗神经管、内耳道及蜗神经影像学对照研究

Measurements of normal cochlear nerve canal,internal auditory canal and cochlear nerve in infants and adults: an imaging study

目的:测量正常婴幼儿和成人蜗神经管(CNC)、内耳道(IAC)及蜗神经(CN)的正常值并观察两组之间有无差异,为婴幼儿期开展人工耳蜗植入术(CI)提供必要依据。方法:选择婴幼儿及成人各30名,均行颞骨HRCT扫描,另选择婴幼儿及成人各20名,均行内耳道MRI FIESTA序列扫描,所有病例均排除内耳疾患。在HRCT图像上分别测量CNC宽度及IAC最大径,在MRI图像上测量CN直径,各测量结果以均值±标准差表示。各测量指标均进行婴幼儿及成人组间比较。结果:正常婴幼儿和成人CNC宽度、IAC最大径及CN直径测量结果分别如下:CNC宽度(1.92±0.25)mm、(1.84±0.19)mm;IAC最大径(4.92±0.69)mm、(5.04±0.59)mm;CN直径(1.06±0.08)mm、(1.02±0.11)mm。以上各测量指标婴幼儿及成人组间均无统计学差异。结论:正常婴幼儿CNC、IAC及CN大小与成人无显著性差异,本研究表明婴幼儿期开展CI是可行的。同时本研究所得到的测量值为蜗神经发育不良(CND)诊断提供了重要参考依据。

Objective： Knowledge of the normal cochlear nerve canal （CNC）, internal auditory canal （IAC） and cochlear nerve （CN） is necessary during preoperative evaluation for cochlear implantation （CI） in infants. The purpose of this work was therefore to measure the dimensions of the CNC, IAC and CN. In addition the mean values （x_＋SD） were compared to analyse the difference between infants and adults. Methods： Thirty infants and thirty adults were studied who had underwent HRCT of the temporal bone. Moreover twenty infants and twenty adults were also studied who had underwent MRI of IAC. No patient had a prior history of sensorineural hearing loss （SNHL） and bony abnormalities of the inner ear. The diameters of IAC and CNC were measured on transverse HRCT. And the diameter of the CN in IAC was measured using 3D FIESTA sequence. Mean values were compared between the ears of infants＇ and adults, and statistical analysis was done. Results： Mean_＋SD measurements （in mm） of these structures in infants and adults were as follow： CNC （transverse section） 1.92±0.25 and 1.84±0.19; IAC 4.92±0.69 and 5.04±0.59; CN 1.06±0.08 and 1.02±0.11. There was no significant difference in all of the measure- ments between infants and adults. Conclusion： There was no difference in the dimensions of CNC, IAC and CN between in- fants and adults.