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HAUSP调控网络在肿瘤的研究进展 被引量：1

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摘要 HAUSP(又称为USP7)是泛素特异性修饰酶家族(ubiquitin specific processing enzymes,USP)成员之一,能催化水解泛素分子C-末端的肽链连接,发挥去泛素化作用,参与调节多种癌蛋白、抑癌蛋白的细胞内水平以及亚细胞定位,影响转录因子活性,在肿瘤的发生、发展中有着重要作用。本文旨对HAUSP调控网络在肿瘤中的研究进展进行综述。
作者 程传东 牛朝诗
机构地区 安徽医科大学附属省立医院神经外科安徽省脑立体定向神经外科研究所脑功能与脑疾病安徽省重点实验室
出处 《中国微侵袭神经外科杂志》 CAS 2013年第2期93-96,共4页 Chinese Journal of Minimally Invasive Neurosurgery
基金 国家自然科学基金项目(编号:81172407)
关键词 脑肿瘤 泛素特异性修饰酶家族 去泛素化 治疗
分类号 R730.2 [医药卫生—肿瘤]
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参考文献20

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二级参考文献9

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中国微侵袭神经外科杂志
2013年 第2期

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