摘要
随着现代生活及医疗水平的提高,蠕虫感染率逐渐下降,缺乏蠕虫的暴露可能是免疫相关性疾病发病日益增多的一个重要环境因素。蠕虫对过敏性疾病及自身免疫性疾病的预防及治疗作用近年受到重视,得到了较多流行病学、实验及临床研究的支持。本文就蠕虫与过敏性疾病、炎症性肠病、多发性硬化、Ⅰ型糖尿病、类风湿性关节炎等免疫性疾病防治方面的研究进展作一综述。
The lack of exposure to helminth infections, as a result of improved living standards and medical conditions, may have contributed to the increased incidence of immune-mediated diseases as an important environmental factor. Basically the increasing epidemiologic studies, experimental and clinical date all support the preventive and therapeutic potential of helminth infections in allergic and autoimmune diseases. In this review, we will introduce the latest research progress on the role of helminth in the prevention and treatment of immune-mediated diseases such as allergic disease, inflammatory bowel disease, multiple sclerosis, type 1 diabetes and rheumatoid arthritis.
出处
《胃肠病学和肝病学杂志》
CAS
2013年第2期116-120,共5页
Chinese Journal of Gastroenterology and Hepatology
