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乙型肝炎病毒相关性肝癌的高危因素分析 被引量:5

The risk factors of hepatitis-B-virus-related hepatocellular carcinoma
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摘要 慢性乙型肝炎病毒(HBV)感染是我国肝细胞肝癌的主要致病因素,乙肝相关性肝癌的高危因素众多,包括乙肝病毒的传播方式、HBeAg的状态、病毒载量、基因型和亚型、基因变异和蛋白变异等。监测这些高危因素有助于筛查原发性肝癌的易感人群,有利于肝癌的早期发现、早期治疗。本文就与乙肝病毒相关的因素作一综述。 Chronic hepatitis B is the main pathogenic factor of hepatocellular carcinoma (HCC) in China. There are many high rick factors of hepatitis B related HCC included the way of HBV transmission, the state of HBeAg, the load of HBV virus, hepatitis B virus gene type and subtype, the variation of gene and protein. Monitoring these high risk factors may help to screen susceptible population of primary hepatic cancer and gain the benefit of early finding and early treatment of primary hepatic cancer. This review summarized the risk factors of HCC among HBV infected individuals and the value of these factors in early diagnosis and treatment.
作者 顾清 王虹
出处 《胃肠病学和肝病学杂志》 CAS 2013年第2期171-174,共4页 Chinese Journal of Gastroenterology and Hepatology
关键词 乙型肝炎病毒 肝细胞肝癌 病毒载量 基因型 基因突变 Hepatitis B virus Hepatocellular carcinoma Viral load Genotype Mutation
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