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低氧诱导因子-1与鼻咽癌关系研究进展 被引量:4

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摘要 许多肿瘤内存在明显缺氧区域,但缺氧状态下的肿瘤细胞仍能不断生长、繁殖和转移。低氧诱导因子-1是调节肿瘤细胞缺氧反应的主要转录因子。目前研究的机制主要包括调节肿瘤细胞代谢、促进肿瘤新生血管形成、促进肿瘤干细胞分化与抗肿瘤细胞凋亡等。本文就低氧诱导因子-1基本生物学特性及其在鼻咽癌领域中的研究进展作一综述。
作者 杨红 姚俊
出处 《中华实用诊断与治疗杂志》 2013年第2期110-112,共3页 Journal of Chinese Practical Diagnosis and Therapy
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二级参考文献63

共引文献50

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