针刺阳陵泉对脑梗死患者被动运动的即刻效应观察

Observation on the immediate effects of acupuncture at Yanglingquan(GB 34) on passive movement in cerebral infarction patients

目的:应用功能磁共振观察针刺阳陵泉对脑梗死偏瘫患者被动运动的中枢即刻效应,为临床治疗该病提供参考依据。方法:使用1.5T磁共振扫描仪,对6例右侧脑梗死恢复期左侧偏瘫患者,在针刺左侧阳陵泉前后被动对指运动时进行功能磁共振扫描,并以假穴针刺作对照,观察其相应脑部的即刻激活部位。结果:所有患者被动运动的激活区集中在右侧运动感觉皮层,与假穴相比,针刺阳陵泉在左侧岛叶前部、额下回、中央前回、梭状回、小脑等区域,中枢效应强于假穴,这些区域涉及多个大脑网络。结论:针刺阳陵泉可能通过调节运动相关网络促进偏瘫恢复。

Objective To observe central immediate effect of acupuncture at Yanglingquan （GB 34） on passive movement of cerebral infarction paitents with hemiplegia by functional magnetic resonance imaging （fMRI） and provide reference for clinical treatment. Methods With 1.5 T MRI scanner, six cases of right cerebral infarction paitents with left hemiplegia in recovery stage were scanned during passive fingers movement before and after acu- puncture at Yanglingquan （GB 34）, which was controlled with sham-acupoint acupuncture to observe immediate activated part of the corresponding brain. Results The activated areas of the passive movement in all the patients were mainly motor sensory cortex on the right side. Compared with sham-acupoint, in the left anterior insula, in- ferior frontal gyrus, central gyrus, fusiform gyrus, cerebellum, acupuncture at Yanglingquan （GB 34） has better central effect. These areas were involved with several brain networks. Conclusion The acupuncture at Yan- glingquan （GB 34） could promote recover of helmiplegia by regulating motor-related network.