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手性磺内酰胺诱导的不对称Diels-Alder反应及其结构与手性诱导的关系

Asymmetric Diels-Alder Reaction Induced by Chiral Sultams and the Relationship Between Structure of Sultam and Chiral Induction
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摘要 Enantiomerically pure sultams (-)-2, (+)-3 and (+)-4 were synthesized.Their uses as new chiral auxiliaries in asymmetric Diels-Alder reactions with diastereoselectivity up to 99∶1 are presented. The relationship between the structure of chiral sultam and the effectiveness of asymmetric induction in Diels-Alder reactions are also discussed. Enantiomerically pure sultams (-)-2, (+)-3 and (+)-4 were synthesized.Their uses as new chiral auxiliaries in asymmetric Diels-Alder reactions with diastereoselectivity up to 99∶1 are presented. The relationship between the structure of chiral sultam and the effectiveness of asymmetric induction in Diels-Alder reactions are also discussed.
出处 《中山大学学报(自然科学版)》 CAS CSCD 北大核心 2000年第4期131-132,共2页 Acta Scientiarum Naturalium Universitatis Sunyatseni
基金 香港浸会大学基金资助项目 香港研究资助局基金资助项目
关键词 磺内酰胺 不对称诱导 DIELS-ALDER反应 手性诱导 sultam chiral auxiliary reagent asymmetric induction Diels-Alder reaction
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参考文献2

  • 1Jiang L S,Tetrahedron Lett,1999年,55卷,2245页
  • 2Chan W H,Tetrahedron Asymmetry,1997年,8期,2501页

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