音乐疗法辅治抑郁症疗效及对生活质量的影响

Effect of music therapy on major depression as an adjuvant approach

目的研究音乐疗法辅治抑郁症的疗效及对生活质量的影响。方法选择符合诊断标准的抑郁症患者86例，分治疗组52例和对照组34例，两纽均给予护理干预和药物治疗，药物治疗使用氟西汀胶囊10mg／d，舒必利200mg／d，治疗1周后氟西汀胶囊加量至20mg／d，舒必利加量至400mg／d，疗程6周；治疗组加用音乐早、中、晚3次，60rain／次；观察两组患者间HAMD评分及生活质量FS—D量表评分差异。结果两组治愈率、显效率、改善率、无效率分别为：88．46％和52．94％、7．69％和26．47％、3．85％和17．62％、0和2．94％，相互间比较差异有统计学意义（P〈0．05）；两组治疗后的心理健康、情绪角色、躯体功能、躯体角色、疼痛、社会功能、活力评分与治疗前比较均有显著提高（P〈0．05），两组间比较，差异无统计学意义（P〉0．05）。结论音乐可干扰人的认知行为，调节情绪，放松心境，提高抗抑郁症药治疗抑郁症的疗效，改善患者的生活质量。

Objective To investigate the therapeutic effect of music therapy on major depression as an adjuvant approach. Methods 86 patients with major depression were included into two groups. All patients were treated with regular nursing and drug treatment but music therapy was added only to therapy group in order to compare with control group. The drugs were fluoxetine caspule（10mg/d） and sulpiride（200mg/d）, The dose of fluoxetine easpule was increased to 20mg/d and sulpiride was increased to 400mg/d after one week. The period of treatment was six weeks. Music therapy was applied in 3 ses- sions in morning, noon and evening. Hamilton Scale of Depression （HAMD） and FS--D were used to assess the efficacy and patients＇ quality of life. Results The cure rate, markedly improved rate, effective rate and non--effective rate in two groups were showed as following： 88.46% vs. 52.94%,7.69% vs. 26.47% ,3.85% vs. 17.62% ,0.00% vs. 2.94%. Significant difference （P 〈 0.05） appeared between two groups. The scores of mental health, emotional role, body function, body role, pain and social func- tion increased significantly after treatment in both groups （P 〈 0.05）. There was no significant differ- ence between the two groups （P 〉 0.05）. Conclusions Music therapy may improve the life quality of patients and enhance the effect of antidepressants in major depression on functions of emotional and cognitive function.