静脉尿路造影不良反应的危险因素

Risk factors of adverse reaction in intravenous urography

目的:探讨静脉尿路造影不良反应的危险因素。方法:回顾总结236例静脉尿路造影患者的一般资料,将患者分为不良反应组(n=21)和无不良反应组(n=215)。对可能引起不良反应的因素进行单因素与logistic回归分析。结果:离子型造影剂、剂量>200mL、注射时间<5min、糖尿病、心理障碍、年龄与静脉尿路造影不良反应有关(χ2/t=9.741、9.314、4.590、9.896、7.235和6.892,P<0.05);应用离子型造影剂(OR=4.402,95%CI=1.510～12.835)、剂量>200mL(OR=3.925,95%CI=1.386～11.109)、注射时间<5min(OR=4.350,95%CI=1.466～12.907)、糖尿病(OR=3.731,95%CI=1.228～11.340)、心理障碍(OR=3.129,95%CI=1.071～9.144)是不良反应的独立危险因素。结论:静脉尿路造影不良反应与造影剂的种类、剂量、注射速度、糖尿病、心理障碍密切相关。

Aim：To investigate the risk factors of adverse reaction in intravenous urography.Methods：The general information of 236 intravenous urography patients was retrospectively summarized and patients were divided into adverse reaction group（n=21） and non-adverse reaction group（n=215）.The factors which might cause adverse reaction were analyzed with single factor analysis and logistic regression analysis.Results：The single factor analysis showed that ionic contrast agent,dose（200 mL）,injection time（5 min）,diabetes,psychologic obstacle,and age were related to adverse reaction in intravenous urography（χ2/t=9.741,9.314,4.590,9.896,7.235,and 6.892,P0.05）.Logistic regression analysis identified that ionic contrast agent（OR=4.402,95%CI=1.510~12.835）,high dose（OR=3.925,95%CI=1.386~11.109）,injection time 5 min（OR=4.350,95%CI=1.466~12.907）,diabetes（OR=3.731,95%CI=1.228~11.340）,psychologic obstacle（OR=3.129,95%CI=1.071~9.144）were the independent risk factors of adverse reaction.Conclusion：Adverse reactions in intravenous urography are closely related to the type,dose,injection speed of contrast agent,diabetes and psychologic obstacle.