联合应用MR扩散加权成像(DWI)和MR波谱成像(MRS)对前列腺癌的诊断价值

Combination of MR Diffusion Weighted Imaging(DWI) and MR Spectroscopic Imaging (MRS) on the Diagnostic Value of Prostate Cancer

目的:探讨DWI(扩散加权MR成像)联合MRS(波谱MR成像)对前列腺癌患者进行诊断的临床意义。方法:对我院自2008年11月至2011年11月以来,于我科检查的64例前列腺癌患者临床资料进行回顾性分析。结果:患者前列腺的ADC值对比,其癌区同非癌区呈显著差异(P<0.05)。患者前列腺癌区的MRS,其Cit峰呈降低表现,其(Cre+Cho)峰呈显著升高表现,其(Cre+Cho)与Cit比值的均值是(1.83 1.54);患者前列腺非癌区MRS,其cit峰呈增高表现,其(Cre+Cho)峰降低,其(Cre+Cho)与Cit比值的均值是(0.82 0.39),呈显著差异(P<0.05)。患者常规MRI具有的敏感性是71.9%,其MRI与MRS结合的敏感性是87.5%,其联合应用DWI与MRS以及MRI的敏感性是93.7%。结论:DWI(扩散加权MR成像)联合MRS(波谱MR成像)对前列腺癌患者进行诊断,同单独应用相较,可以显著提高检出敏感性,应依据患者具体情况合理推广。

Objective：Investigate DWI（diffusion-weighted MR imaging） combined MRS （spectroscopy MR imaging） the diagnosis of prostate cancer patients.Methods：A retrospective analysis of 64 cases of prostate cancer patients in our hospital from November 2008 to November 2011,my department to check clinical data.Results：ADC value comparison of patients with prostate cancer District,with the non-cancerous area was a significant difference（P0.05）.The MRS of patients with prostate cancer,its Cit peak was lower performance（Cre＋Cho） peak was significantly higher performance（Cre＋Cho）,and Cit ratio of the mean （1.83±1.54）;patients with prostate cancer District MRS,cit peak was increased performance,reduce its（Cre＋Cho） peak（Cre＋Cho）,and cit ratio of the mean （0.82 soil 0.39）,showed a significant difference（P0.05）.Patients with conventional MRI has a sensitivity of 71.9%,its combination of MRI and MRS sensitivity was 87.5%,and their joint application of DWI and MRS and MRI sensitivity was 93.7%.Conclusion：DWI（diffusion weighted MR imaging） and MRS （Magnetic Resonance MR imaging） for diagnosis of prostate cancer patients,compared with a separate application can significantly improve the detection sensitivity,reasonable promotion should be based on the condition of the patients.