肝胆外科手术部位感染（SSI）的病原菌和药敏分析

Distribution of Pathogens and Drug Susceptibility Tests from Surgical Site Infection in Hepatobiliary Surgery

目的探讨肝胆外科手术部位感染（surgicalsiteinfection，SSI）影响因素、病原茵分布情况和感染预防措施。方法对2008年1月～2010年12月期间，湖北省黄冈地区肝胆外科手术部位（SSI）住院送检的10264例标本进行培养，并采用BECKMANCOULT全自动细菌分析系统鉴定分离菌，K—B纸片扩散法进行药敏试验，以CLSl2009年版标准判读结果。结果从10264份送检标本中检出病原茵1416株，阳性率为13．8％；其中革兰氏阳性茵524株，占37％，革兰氏阴性菌892，占63％。结论大肠埃希茵、金黄色葡萄球菌等是造成肝胆外科手术部位感染的主要病原菌。合理使用抗生素对于有效预防和控制手术部位感染（surgicalsiteinfection，SSI）至关重要。

Objective To discuss the distribution, drug resistance and preventing measures of the pathogenic microbiology of surgical site infection（SSI） in hepatobiliary and gall surgery in Hubei Huanggang. Methods Collected the specimen which came from the inpatient in the departments of liver and gall surgical SSI of Hubei Huanggang from 2008 to 2010 ,and isola- ted and identified the bacteria using the Beckman Coult System, used the Kirby-Bauer to do the drug sensitive test with CLSI2009 as a standard. Results There were 1 416 bacterial strains （gram-positive bacteria accounts for 37% while gram- negative accounts 63 %） in 10 264 specimen, the positive rate was 13.8 %. The common bacteria were enterobacters, Staphy- lococcus pyogenes aureus, Enterococeus and coagulase negative staphylococci. Conclution Enterobacter, Staphylococcus pyogenes aureus,Enterococcus and coagulase negative staphylococci are the major bacteria of SSI in the departments of liver and gall surgical in Hubei Huanggang,the prevalences are differences in di{ferent surgical position,and the percent of infec- tion can reduce by effective preventive measures.