神经干细胞活体示踪的研究现状与前景
Cueeent status and prospect about in vivo tracking neural stem cells
摘要
神经干细胞（neuralstemcells，NSCs）是一类具有自我更新能力和多分化潜能的细胞，在一定的条件可分化为神经元、星形胶质细胞和少突胶质细胞。近年来，NSCs移植治疗神经系统疾病中的有效性和潜能日益受到重视，已在诸多中枢神经系统疾病显现出独特的优势，具有广阔的应用前景[1-3]。但NSCs移植治疗的疗效机制目前仍不详。为了明确NSCs移植后症状改善的原因，了解细胞移植后的生存状态，区分移植细胞和宿主细胞，监测移植后NSCs在宿主内的活力、分化、迁移、代谢机制以及整合情况，需要对移植的NSCs进行非侵袭性活体示踪。
出处
《中华神经医学杂志》
CAS
CSCD
北大核心
2013年第2期203-206,共4页
Chinese Journal of Neuromedicine
基金
国家自然科学基金（30973225）
关键词
神经干细胞
细胞移植
分子影像学
Neural stem cell
Cell transplantation
Molecular imaging
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