磁敏感加权成像技术评估正常人群脑静脉血相位值

Assessment of cerebral venous phase values in healthy adults with susceptibility-weighted imaging

目的利用SWI测量正常人群脑静脉血相位值,评价不同年龄组及不同血管的静脉血相位值。方法对96名健康受试者行常规MR、SWI检查,对大脑内静脉、基底静脉、大脑中浅静脉、上矢状窦、小脑静脉、脑干前正中静脉的静脉血相位值进行测量。比较5个年龄组(20～29岁、30～39岁、40～49岁、50～59岁、60～69岁)间及不同血管之间静脉血相位值的差异。结果各测量血管的静脉血相位值在不同年龄组间差异均无统计学意义(P均>0.05)。上矢状窦的血液相位值(-0.644±0.079)在各测量血管中最低(P均<0.05),而小脑静脉和脑干前正中静脉相位值较高(-0.473±0.089、-0.354±0.075,P均<0.05)。结论脑静脉血相位值随年龄改变无明显变化,而不同静脉血相位值存在差异。

Objective To measure cerebral venous phase values in healthy adults with SWI, and to evaluate the variation of venous phase values by age and drainage territory. Methods Totally 96 healthy volunteers underwent conventional MRI and SWI. Blood phase values of specified veins, including internal cerebral vein, basal vein, superficial middle cerebral vein, superior sagittal sinus, cerebellar vein as well as median anterior vein of brainstem were measured. The phase values among different age groups （20—29 years old, 30—39 years old, 40—49 years old, 50—59 years old and 60—69 years old）, as well as among different veins were compared. Results No significant difference of venous phase values was found among different age groups （all P〉0.05）. Phase value of superior sagittal sinus （-0.644±0.079） was the lowest among all specified vessels （all P〈0.05）, whereas cerebellar vein and median anterior vein of brainstem （-0.473±0.089, -0.354±0.075） had higher phase values than other veins （all P〈0.05）. Conclusion There is no age-related change for cerebral venous phase values. Blood phase values are various in different cerebral venous structures.