重组人表皮生长因子凝胶与康复新液治疗Ⅲ级放射性皮炎的疗效观察

Observation on efficacy of recombinant human epidermal growth factor gel and Kangfuxin liquid in treating Ⅲ radiodermatitis

目的观察重组人表皮生长因子凝胶与康复新液治疗Ⅲ级放射性皮炎的临床效果。方法将放射治疗过程中发生Ⅲ级放射性皮炎患者24例随机均分为2组。治疗组使用重组人表皮生长因子凝胶与康复新液对损伤部位进行换药,对照组使用1%冰片对损伤部位进行换药,2组均暴露皮肤。感染者全身使用抗生素治疗。结果治疗组平均创面愈合时间(4.0±1.5)d,对照组平均创面愈合时间(7.8±3.5)d。结论重组人表皮生长因子凝胶与康复新液用于临床治疗Ⅲ级放射性皮肤损伤效果明显,愈合时间短,可减轻和控制局部疼痛,提高患者的生活质量。

Objective To observe the clinical effect of recombinant human epidermal growth factor （RHEGF） gel and Kangfuxin liquid in treating Ⅲ radiodermatitis. Methods Twenty -four patients encountered Ⅲ radiodermatitis in the process of radiotherapy were randomly divided into two groups, in which RHEGF gel and Kangfuxin liquid were applied on the injury parts in treatment group, and 1% borneol was used in control group. The skin was exposed to the air in both groups, and infected people were treated by applying antibiotics on the whole body. Results The average healing time of the treatment group wound surface was （4.0 ± 1.5 ） d while that of control group wound surface being （7.8 ± 3.5 ） d. Conclusion In clinic, the combination of RHEGF gel and Kangfuxin liquid has significant effects and short healing time in treating Ⅲ radioactive skin damage, and they can alleviate and control local pain to improve the life quality of pa- tients.