携带式微量注射泵治疗铁过载的护理体会

Nursing experience of portable micro-injection pump in the treatment of iron overload

目的总结皮下注射去铁胺治疗输血依赖性铁过载的护理体会。方法采用携带式微量注射泵为55例输血相关性铁过载患者皮下注射甲磺酸去铁胺进行治疗并采取相关护理。结果 55例患者血清铁蛋白均较治疗前下降;10例因铁过载致继发血糖升高患者治疗后血糖均降至正常水平,皮肤色素沉着变淡;33例患者红细胞输注间隔时间延长;所有患者副反应轻微,2例患者出现皮下硬结,2例患者出现发热,其中1例因败血症而中断治疗。结论皮下注射去铁胺治疗输血依赖性铁过载疗效高、安全性好,护理人员对输血患者进行健康教育并建立祛铁治疗档案可提高患者的依从性和治疗连续性。

Objective To summarize the nursing experience of subcutaneous injection of deferoxamine in the treatment of patients with transfusion - dependent iron overload. Methods Portable micro - injection pumps were used for injecting deferoxamine mesylate subcutaneously in the treatment of 55 patients with transfusion - related iron overload, and corresponding nursing was implemented as well. Results After treatment, the lever of serum ferritin （SF） decreased than before treatment in 55 patients, and lever of blood glucose decreased to normal level as well as skin pigmentation faded in 10 patients with iron overload- induced secondary hyperglycemia; interval time of erythrocyte transfusion prolonged in 10 patients; all the patients had mild side effects, 2 patients had subcutaneous indurations; 2 patients had fever, and one of them discontinued treatment due to septicemia. Conclusion For the treatment of transfusion- dependent iron overload, subcutaneous injection of deferoxamine is effective and safe. Nursing personnels should help patients to understand health education and establish documents of iron dispelled therapy, which can improve patients＇ compliance and continuity of treatment.