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Ethylenediamine: A Highly Effective Catalyst for One-Pot Synthesis of Aryl Nitroalkenes via Henry Reaction and Dehydration

Ethylenediamine: A Highly Effective Catalyst for One-Pot Synthesis of Aryl Nitroalkenes via Henry Reaction and Dehydration
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摘要 Ethylenediamine (H2NCH2CHeNH2) was found to be a highly effective catalyst for the condensation of aryl aldehydes with nitromethane (or nitroethane). When 1%-2% (tool%) of ethylenediamine was used as the catalyst, the one-pot reaction of aryl aldehydes with nitromethane (or nitroethane) by refluxing for 3-10 h efficiently afforded various arylnitroalkenes la-ly in 85%-97% yields. Ethylenediamine (H2NCH2CHeNH2) was found to be a highly effective catalyst for the condensation of aryl aldehydes with nitromethane (or nitroethane). When 1%-2% (tool%) of ethylenediamine was used as the catalyst, the one-pot reaction of aryl aldehydes with nitromethane (or nitroethane) by refluxing for 3-10 h efficiently afforded various arylnitroalkenes la-ly in 85%-97% yields.
出处 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2012年第12期2827-2833,共7页 中国化学(英文版)
基金 the National Natural Science Foundation of China (No. 20972048) and Shanghai Educational Development Foundation (The Dawn Program: No. 03SG27) for the financial support of this work.
关键词 ETHYLENEDIAMINE NITROALKENE NITROMETHANE nitroethane aryl aldehyde ethylenediamine nitroalkene nitromethane nitroethane aryl aldehyde
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  • 1Bates, D. J. P.; Smitherman, R K.; Townsend, A. J.; King, S. B.; Morrow, C. S. Biochemistry 2011, 50, 7765.
  • 2Tang, X.; Guo, Y.; Nakamura, K.; Huang, H.; Hamblin, M.; Chang, L.; Villacorta, L.; Yin, K.; Ouyang, H.; Zhang, J. Biochem. Biophys. Res. Commun. 2010, 397, 239.
  • 3Gorczynski, M. J.; Smitherman, R K.; Akiyama, T. E.; Wood, H. B.; Berger, J. P.; King, S. B.; Morrow, C. S. J. Med. Chem. 2009, 52, 4631.
  • 4Wang, W.-Y.; Hsieh, P.-W.; Wu, Y.-C.; Wu, C.-C. Biochem. Pharmacol. 2007, 74, 601.
  • 5Gorczynski, M. J.; Huang, J.; Lee, H.; King, S. B. Bioorg. Med. Chem. Lett. 2007, 17,2013.
  • 6Milhazes, N.; Calheiros, R.; Marques, M. P. M.; Garrido, J.; Cordeiro, M. N. D. S.; Rodrigues, C.; Quinteira, S.; Novais, C.; Peixe, L.; Borges, F. Bioorg. Med. Chem. 2006, 14, 4078.
  • 7Mohan, R.; Rastogi, N.; Namboothiri, I. N. N.; Mobin, S. M.; Panda, D. Bioorg. Med. Chem. 2006, 14, 8073.
  • 8Gorczynski, M. J.; Huang, J.; King, S. B. Org. Lett. 2006, 8, 2305.
  • 9Boyce, G. R.; Liu, S.; Johnson, J. S. Org. Lett. 2012, 14, 652.
  • 10Dong, W.; Xu, D.; Xie, J. Chin. J. Chem. 2012, 30, 1771.

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