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肿瘤相关巨噬细胞(TAM)对肿瘤发生发展的影响

The Effects of tumor Associated Macrophage (TAM) on Cancer Development
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摘要 实体肿瘤微环境一直处于复杂的慢性炎性状态中,其周围充满丰富的炎性介质、炎性细胞,以及调控紊乱的血管系统和蛋白水解酶类。肿瘤相关巨噬细胞(tumor-associated macrophage,TAM)作为肿瘤相关炎症的主要参与者,它在促进肿瘤细胞增殖侵袭和迁移、新生血管形成以及产生免疫抑制等方面的功能对癌症的发生发展产生重要影响。因此针对TAM的深入研究具有重要的科学意义和临床价值,为肿瘤的治疗开辟新的思路和途径。 Solid tumor microenvironment is characterized by its passive inflammation conditions, with abundant mediators and inflammatoing angiogenesis as well as immunosuppression. For this reason, intensive study of TAM will produce scientific significances and clinical values
作者 王任
出处 《中国化工贸易》 2013年第1期146-147,共2页 CHINA CHEMICAL TRADE
关键词 肿瘤相关巨噬细胞 肿瘤发生发展 TAM tumor development
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参考文献29

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