子囊菌延长因子1 alpha基因密码子偏好性分析(英文)

Codon Usage and Bias of Elongation Factor 1 Alpha Gene in Ascomycota

文中对子囊菌代表类群的延伸因子1 alpha基因密码子的使用模式进行了研究。结果表明:该基因的密码子使用偏好性不仅与核酸碱基组成密切相关,也受到其他选择性压力的影响。统计分析揭示了子囊菌各类群该基因的密码子组成和编码特点,在同义密码子的选择模式上,酵母纲(Saccharomycetes)的成员具有较独特的偏好性。基于密码子用法分歧度的聚类分析方法较合理地反映了大部分类群的分类学地位,但在各个纲的内部,密码子偏好性的变化程度存在差异。

The codon usage of elongation factor 1 alpha gene in some taxa of Ascomycota was analyzed in this study. The results showed a high frequency of codons ending with G or C in most taxa except for the species of Saccharomycetes. The codon choice of this gene was dependent on base composition of nu- cleotide sequences, and was also attributed to other functional constraints. A detailed comparison of RSCU values demonstrated a certain difference of codon bias among 22 taxa. The members of Saccha- romyeetes displayed a distinctive pattern of codon usage, compared to other taxa. The current results also indicated that the degree of variation in eodon usage among classes of Aseomyeota might be different.