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面部整形手术局部浸润麻醉下的丙泊酚镇静深度 被引量:1

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摘要 目的探讨丙泊酚靶控输注(TCI)用于局部浸润麻醉下面部整形手术镇静的可行性,并寻找达到满意镇静时的半数有效血浆靶浓度(Ce50)。方法面部整形患者40例,在咪达唑仑和芬太尼镇静镇痛下,以血浆靶浓度为1μg/ml开始TCI丙泊酚,使改良镇青争/警醒评分(OAA/S评分)达到2~3分为满意镇静标准,相邻靶浓度比率为1:2观察局部浸润麻醉时、切皮时、手术30min时患者OAA/S评分变化及术后患者对手术过程记忆和满意评价。结果丙泊酚TCI达到满意镇静深度时的Ce50为1.08μg/ml,95%的可信区间CI为1.38~3.76μg/ml。在局部浸润麻醉时OAA/s评分升高,切皮和手术中评分无变化,手术后部分患者对麻醉和切皮有记忆,大部分患者对手术过程满意。结论丙泊酚TCI能够满足局部浸润麻醉下门诊整形手术的镇静需求,提高就诊患者的满意度。达到OAA/S评分2—3分的满意镇静深度的Ce50为1.08μg/ml。
作者 张同寅
出处 《中国实用医刊》 2013年第5期99-100,共2页 Chinese Journal of Practical Medicine
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