环孢素治疗狼疮肾炎疗效观察
摘要
系统性红斑狼疮(SLE)是一种累及多个系统的自身免疫病,临床上肾脏受累60%~80%,糖皮质激素联合环磷酰胺是治疗狼疮肾炎的主要药物,但因环磷酰胺(CTX)的不良反应较大,有可能给患者带来骨髓抑制、性腺抑制、感染、
参考文献4
-
1陈小建,施辛.环磷酰胺治疗系统性红斑狼疮方案探讨[J].中国皮肤性病学杂志,2011,25(11):899-902. 被引量:4
-
2林善锬.继发性肾小球疾病诊治中的几个重要问题[J].中国实用内科杂志,2002,22(9):513-514. 被引量:14
-
3Smith MP,Newstead CG,Ahmad N. Poor tolerance of sirolimus in a steroid avoidance regimen for renal transplantation[J].Transplantation,2008.636-639.
-
4Yao XD,Chen HP,Wang QW. Cyclosporin A treatment for idiopathic membranous nephropathy[J].Chinese Medical Journal(Engl),2001,(12):1305-1308.doi:10.3760/j.issn:0366-6999.2001.12.018.
二级参考文献27
-
1Donadio JV, Holley KE, Ferguson RH, et al. Treatment of diffuse proliferative lupus nephritis with prednisone and combined prednisone and cyclophosphamide [ J ]. N Engl J Med, 1978, 299 (21): 1151 - 1155.
-
2Austin HA Ⅲ, Klippel JH, Balow JE. Therapy of lupus nephritis: controlled trial of prednisone and cytotoxic drugs [ J ]. N Engi J Med, 1986, 314(10) :614 -619.
-
3Boumpas DT, Austin HA Ⅲ, Vaughn EM,et al. Controlled trial of pulse methylpred- nisolone versus two regimens of pulse cyclophosphamide in severe lupus nephritis [ J ]. Lancet , 1992, 340 (8822) : 741 - 745.
-
4Saito M, Aogi K, Sekine I , et al. Palonosetron plus dexamethasone versus granisetron plus dexamethasone for prevention of nausea and vomiting during chemotherapy: a double-blind, double-dummy, randomised, comparative phase III thai [ J ]. Lancet Oncology, 2009, 10(2): 115 - 124.
-
5Yee CS, Gordon C, Dostal C, et al. EULAR randomised controlled trial of pulse cyclophosphamide and methylprednisolone versus continuous cyclophosphamide and prednisolone followed by azathioprine and prednisolone in lupus nephritis [ J ]. Ann Rheum Dis,2004, 63(5) : 525 -529.
-
6Ruiz-lrastorza G, Olivares N, Ruiz-Arruza 1, et al. Predictors of major infections in systemic lupus erythematosus[ J]. Arthritis Res Ther,2009, 11(4):R109.
-
7Gonzalez LA, Pons-Estel GJ, Zhang JS, et al. Effect of age, menopanse and cyclophosphamide use on damage accrual in systemic lupus erythematosus patients from LUMINA, a multiethnic US cohort (LUMINA LXIII ) [J]. Lupus,2009,18(2):184-186.
-
8Appenzeller S, Blatyta PF, Costallat LTL. Ovarian failure in SLE patients using pulse cy- clophosphamide: comparison of different regimes[J]. Rheumatol Int,2008, 28 (6) : 567 - 571.
-
9Somers EC, Marder W, Christman GM, et al. Use of a gonadotropin-releasing hormone analog for protection against premature ovarian failure during cyclophosphamide therapy in women with severe lupus [ J ]. Arthritis Rheum,2005, 52(9): 2761 -2767.
-
10Bernatsky S, Boivin J, Lawrence J, et al. An international cohort study of cancer in systemic lupus erythematosus [ J ]. Arthritis Rheum, 2005,52 (5) : 1481 - 1490.
共引文献16
-
1林善锬.糖尿病肾病发病机制的几个关键[J].中华老年多器官疾病杂志,2002,1(3):165-167. 被引量:3
-
2马胜银,刘朝阳.狼疮性肾炎的治疗新进展[J].蚌埠医学院学报,2005,30(2):188-188. 被引量:2
-
3楼红玫.科素亚与洛汀新治疗糖尿病肾病临床观察[J].现代中西医结合杂志,2005,14(14):1858-1858. 被引量:3
-
4何平,苏雪松,刘大军.苯那普利联用氯沙坦治疗糖尿病肾病的疗效观察[J].实用药物与临床,2006,9(3):155-156. 被引量:1
-
5吴歌.甲基强的松龙联合百令胶囊治疗狼疮性肾炎疗效观察[J].医药论坛杂志,2007,28(17):38-39. 被引量:5
-
6周建敏,姚国卫,郭文建.厄贝沙坦联合苯那普利治疗糖尿病肾病的疗效观察[J].山西医药杂志(上半月),2008,37(2):156-157. 被引量:1
-
7李树岗,宋远瑛.补肾活血汤联合来氟米特治疗狼疮性肾炎临床疗效分析[J].安徽中医学院学报,2008,27(6):17-20. 被引量:4
-
8李树岗,宋远瑛.他汀类药物联合来氟米特治疗狼疮性肾炎临床疗效分析[J].实用临床医药杂志,2009,13(4):68-70. 被引量:1
-
9李树岗,宋远瑛.他汀类药物联合来氟米特治疗狼疮性肾炎临床疗效分析[J].实用临床医药杂志,2009,13(5):61-62. 被引量:2
-
10王小谦.来氟米特治疗狼疮性肾炎疗效观察52例[J].中国医药指南,2010,8(23):111-112. 被引量:3
-
1邓立武.参芪衍宗汤早期干预环磷酰胺性腺抑制的疗效观察[J].中国中西医结合肾病杂志,2010,11(6):533-534. 被引量:1
-
2陈小建,施辛.环磷酰胺治疗系统性红斑狼疮方案探讨[J].中国皮肤性病学杂志,2011,25(11):899-902. 被引量:4
-
3陈小建(综述),施辛(审校).环磷酰胺在系统性红斑狼疮治疗中的方案研究[J].苏州医学,2011,34(1):49-53.
-
4张衍仕,陈成邦,邓云,付乃雄.他克莫司与环磷酰胺治疗狼疮性肾炎的临床比较[J].广西医学,2011,33(5):583-585. 被引量:11
-
5徐耀文,陈楠,陈晓农,任红,张文,潘晓霞,郝翠兰,傅秀兰.霉酚酸酯与环磷酰胺冲击治疗狼疮性肾炎临床疗效的比较[J].中华肾脏病杂志,2002,18(1):21-24. 被引量:37
-
6李宏,仲跻明,周海洋,范兴忠.雷公藤多苷治疗肾小球疾病不良反应观察[J].药物不良反应杂志,2000,2(1):25-27. 被引量:2
-
7徐婧,张丹,张卓莉.环磷酰胺在治疗系统性自身免疫病中不良反应的研究[J].中华风湿病学杂志,2015,19(6):392-395. 被引量:9
-
8周毅,杨学莉,杨岫岩,梁柳琴,许韩师.对环磷酰胺性腺抑制的狼疮肾炎23例治疗探讨[J].新医学,2003,34(5):301-303. 被引量:1
-
9苗冬蕾,栾永安,李慧娟,钟婉秋,张春艳.口服大剂量环磷酰胺与泼尼松致不良反应临床分析并文献复习[J].中国医刊,2015,50(11):98-100. 被引量:7
-
10杨金华,闫成兰,赵文鹏,赵向聪,吴萌,罗静,曹培龙,李小峰,陈俊伟.免疫净化冲击治疗重症狼疮的临床研究[J].中国药物与临床,2015,15(7):970-971.