柴胡疏肝散加减治疗慢性胆囊炎60例临床研究

Clinical Observation of Modified Powder of Chai-hu Shu-gan on Chronic Cholecystitis,A Report of 60 cases

目的:观察柴胡疏肝散加减治疗慢性胆囊炎的临床疗效。方法:将120例患者随机分为两组,治疗组和对照组各60例。治疗组予以柴胡疏肝散治疗,对照组予以茴三硫片治疗,两组疗程均为4周。结果:治疗组治愈14例,显效22例,有效19例,无效5例,总有效率为91.67%(95%CI=84.68%～98.66%);对照组治愈9例,显效17例,有效21例,无效13例,总有效率为78.33%(95%CI=67.91%～88.75%);两组综合疗效比较(u=2.060 5,P=0.040 7),差异有显著性意义。结论:柴胡疏肝散加减治疗慢性胆囊炎的疗效优于茴三硫片,其收益为OR=0.33(95%CI=0.11～0.99),NNT=7(95%CI=3.8～178.6)。

Objective ： To observe the effect of modified Powder of Chai-hu Shu-gan on chronic choleeystitis. Methods： 120 cases were randomly divided into two groups, and 60 cases in each group. The treatment group was treated with Powder of Chai-hu Shu-gan, and the control group was treated with anethol trithione. One treatment course included 4 weeks. Results： In treatment group 14 cases were recovered, 22 ones excellent, 19 ones effec- tive, and 5 ones ineffective. The total effective rate was 91.67% （95% CI = 84. 68% -98.66% ）. In control group 9 cases was recovered, 17 ones excellent, 21 ones effective, and 13 ones ineffective. The total effective rate was 78.33% （95% CI = 67.91% - 88.75% ）. There was significant difference between the two groups （u = 2. 060 5, P = 0. 040 7 ）. Conclusion ： Modified Powder of Chai-hu Shu-gan has better effect on chronic eholecysti- tis than Tablet of anethol trithione, OR = 0. 33 （95%CI =0. 11 -0. 99）, NNT =7 （95%CI =3.8 - 178.6）.