坎地沙坦片治疗慢性心衰117例临床观察

The clinical observation of Candesartan Cilexetil Tablets treatment of chornic heart failure

目的观察坎地沙坦片改善心力衰竭的疗效。方法慢性心力衰竭患者随机分为观察组60例与对照组57例,观察组采用坎地沙坦片治疗,对照组采用美托洛尔治疗;对比两组的NYHA疗效与Boston心衰计分评价。结果 NYHA心功能疗效观察组总有效率为96.7%,对照组86.0%;Boston心功能疗效观察组治疗组总有效率88.3%,对照组85.9%;组间比较两组疗效无显著性差异(P>0.05)。结论坎地沙坦片治疗慢性心力衰竭总体疗效趋势优于美托洛尔,两者疗效基本相当。

Objective To observe the treatment effect and safety of candesartan cilexetil tablets improving heart failure. Methods 117 cases of patients with heart failure were divided randomly into treatment group（60 cases） and control group（ 57 cases）.Treatment group was treated with Candesartan Cilexetil Tablets,while control group was treated with metoprolol tartrate tablets.The NYHA effect and Boston heart failure scoring effect of two groups were compared. Results As to the NYHA heart function effect,the total efficient rate of treatment group was 96.7% ,while that of control group was 86.0%.As to the Boston heart function effect,the total efficient rate of treatment group was 88.3% ,while that of control group was 85.9%.There was no significant difference in other observing indexes of two groups.Conclusion Candesartan cilexetil tablets and metoprolol tartrate tablets has the considerable treatment effect in improving heart failure.