高龄食管癌患者术后肺部并发症相关因素分析

Related factors of post operative pulmonary complication after esophagectomy in elderly patients with esophageal carcinoma

目的探讨高龄食管癌患者术后肺部并发症的相关因素。方法回顾性分析244例高龄食管癌患者的临床资料,根据是否有术后肺部并发症分为观察组(肺部并发症组)和对照组(无肺部并发症组),并分析其相关因素。结果术后发生肺部并发症患者74例(30.3%);两组患者在性别、年龄及手术入路等方面差异无统计学意义(P>0.05)。吸烟、合并疾病≥2种、术前肺功能较低(FEV1占预计值<50%)、术中输液量较多、手术时间较长、吻合口平面在主动脉弓以上患者的术后肺部并发症发生率相对较高(P<0.05)。结论高龄食管癌患者术后肺部并发症发生率较高,临床医生需根据患者不同情况给予正确指导及积极处理,并不断提高手术操作水平,以降低术后肺部并发症的发生率,提高患者术后生存质量。

Objective To discuss the related factors of post operative pulmonary complication after esophagectomy in elderly patient with esophageal carcinoma.Methods 244 patients＇ clinical data were retrospectively analyzed,and devided into the observation group（with pulmonary complication）and the control group（without pulmonary complication）.Results There were 74 patients diagnosed with pulmonary complication（30.3%）;there was no significantly differences in gender,age,or surgical approach（P0.05）,but significantly differences in smoking,comorbidities,preoperative pulmonary function,intraoperative fluid volume,operation time,and anastomotic plane（P0.05）.Conclusions The incidence of postoperative pulmonary complications in elderly patients with esophageal cancer is high,clinicians need to give proper guidance to the patients according the different situations and active treatment,and constantly improve the level of surgical procedures,in order to reduce the incidence of postoperative pulmonary complications and improve the quality of survival patients.