乳腺癌患者生活质量的调查研究

The investigation of influencing factors in quality of life of breast cancer patients

目的探讨影响乳腺癌患者生活质量的因素。方法收集2008至2011年间在中国医学科学院肿瘤医院确诊的126例来自门诊及病房的乳腺癌患者。选择乳腺癌患者生命质量测定量表(FACT-B)进行横断面问卷调查。统计学方法采用ANOVA及独立样本t检验,检测组间各个变量之间的差异。结果对126例乳腺癌患者根据年龄、婚姻和谐程度、受教育程度、工种、工作压力、工作年限、月收入、每天工作时长和确诊时间等因素进行分层。分别从生理状况、社会/家庭状况、情感状况、功能状况、附加关注等5个方面进行评分。最终发现年龄、受教育程度、月收入、婚姻和谐程度及确诊时间与患者生活质量明显相关。结论在乳腺癌患者的社会人口学因素中,年龄、教育背景、月收入、婚姻和谐程度及确诊时间是影响患者生活质量的主要因素。认识这些差异,有助于今后更有针对性地对患者进行治疗和宣教。

Objective To explicit the influencing factors in quality of life of breast cancer patients.Methods Data were collected from 126 cases both from outpatients and inpatients who were diagnosed with breast cancer during 2008-2011 in Cancer Hospital Chinese Academy of Medical Sciences.FACT-B（functional assessment of cancer therapy-breast）questionnaire was used to conduct this cross-sectional survey.Analysis of variance（ANOVA）and independent t-test were performed to compare different groups regarding QOL subscales.Results The items in FACT-B including physical well-being,social well-being,emotional well-being,functional well-being and breast cancer subscales were scored respectively according to the stratification by age,marriage harmonious degree,education status,type of work,work pressure,work seniority,monthly income,daily working time and time since diagnosis in 126 patients.We identified several factors including age,educational status,monthly income,marriage harmonious degree and time since diagnosis which were obviously relevant to quality of life.Conclusions In various influencing factors of patients with breast cancer,age,educational status,monthly income,marriage harmonious degree and time since diagnosis were the main factors to influence quality of life.It would be more personalized in our treatment and education when concerning the differences.