摘要
衣原体是一类专性细胞内寄生的原核细胞型微生物,感染人体后可引起多种慢性疾病。衣原体在宿主细胞中复制和持续性存在是其致病的主要原因。近年的研究表明,衣原体通过改变MHC抗原表达、干扰宿主细胞凋亡信号通路等机制以逃逸宿主的免疫清除。
Chlamydia is a type of obligate intracellular prokaryotic microorganisms,which can cause many kinds of serious diseases in human.Duplication and persistent survival in host cells is its main pathogenic mechanism.In recent years,studies have shown that Chlamydia can escape host immune recognition and clearance by altering the MHC antigen expression and interfering the apoptosis signal pathway.
出处
《微生物学免疫学进展》
2012年第6期64-67,共4页
Progress In Microbiology and Immunology
基金
国家自然科学基金(鹦鹉热嗜衣原体持续性感染的分子机制研究
31270218)
