1Wang X,Wang H,Xu L. Singificant neuroprotection against ischemic brain injury by inhibition of the MEK1 protein kinase in mice:exploration of potential mechanism associated with apoptosis[J].Journal of Pharmacology and Experimental Therapeutics,2003.172-178.
2Takagi Y,Nozaki K,Sugin T. Phosphorylation of c-JunNH(2)-terminal kinase and p38 mitogen-activated protein kinase aster transient forebrain ischemia in mice[J].Neuroscience Letters,2000.117-120.
6Guo WP,Fu XG,Jiang SM. Neuregulin-1 regulates the expression of Akt,Bcl-2,and Bad signaling after focal cerebral ischemia in rats[J].Biochemistry and Cell Biology-Biochimie et Biologie Cellulaire,2010.649-654.
7Hu J,Chai Y,Wang Y. PI3K p55γ promoter activity enhancement is involved in the anti-apoptotic effect of berberine against cerebral ischemia-reperfusion[J].European Journal of Pharmacology,2012.132-142.
8Noshita N,Lewen A,Sugawara T. Evidence of phosphorylation of Akt and neuronal survival after transient focal cerebral ischemia in mice[J].Journal of Cerebral Blood Flow and Metabolism,2001,(12):1442-1450.doi:10.1097/00004647-200112000-00009.
9Jin R,Yu S,Song Z. Phosphoinositide 3-kinase-gamma expression is upregulated in brain microglia and contributes to ischemia-induced microglial activation in acute experimental stroke[J].Biochemical and Biophysical Research Communications,2010.458-464.
10Jiang Z,Zhang Y,Chen XQ. Apoptosis and activation of ERK1/2 and Akt in astrocytes postischemia[J].Neurochemical Research,2003.831-837.
4Janardhan V,Qureshi AI.Mechanisms of ischemic brain injury[J].Curr Cardiol Rep,2004,6(2):117-123.
5Erdo F,Trapp T,Mies G,et al.Immunohistochemical analysis of protein expr-ession after middle cerebral artery occlusion in mice[J].Acta Nenropathol,2004,107(2):127-136.
6Cattaneo E,Conti L,De FC.Signalling through the JAK-STAT pathway in the developing brain[J].Trends Neurosci,2000,22(8):365-369.
7Justicia C,Gabriel C,Planas AM.Activation of the JAK/STAT pathway follow-ing transient focal cerebral ischemia:signaling through JAK1 and STAT3 in astrocytes[J].Glia,2000,30(3):253-270.
8Satriotomo I,Bowen KK,Vemuganti R.JAK2 and STAT3 activation contributes to neuronal damage following transient focal cerebral ischemia[J].J Neurochem,2006,98(5):1353-1368.
9Suzuki S,Tanaka K,Nogawa S,et al.Phosphorylation of signal transducer and activator of transcription-3 (Stat3) after focal cerebral ischemia in rats[J].Exp Neurol,2001,170(1):63-71.
10Tanaka E, Uehikado H, Niiyama S, et al. Extrusion of intra- cellular calcium ion after in vitro ischemia in the rat hipp- ocampal CA1 region [ J ]. J Neurophysiol, 2002, 88 (2) : 879.