溶栓治疗脑梗死96例临床分析

Thrombolytic therapy for cerebral infarction：clinical analysis of 96 cases

目的 探讨脑梗死患者溶栓治疗的临床疗效。方法 脑梗死患者208例随机分为两组,96例接受溶栓治疗（溶栓组）,112例接受传统常规治疗（常规组）,比较两组临床疗效。结果 溶栓组治疗后神经功能缺损评分（NIHSS评分）比常规组下降趋势更为明显。溶栓组治疗前与治疗后各阶段的NIHSS评分差异均有统计学意义（t=6.05、5.03、6.96、7.94,均P〈0.01）;溶栓组与常规组治疗后90 d预后 Barthel指数差异有统计学意义（t=4.67,P〈0.05）。溶栓组显效率为91.67%,高于常规组的73.21%（χ2=13.47,P〈0.05）。结论 溶栓治疗对脑梗死患者术后生活质量的影响很大,能够明显改善患者神经功能,恢复生活能力,提高生活质量。

Objective To investigate the thrombolytic therapy in patients with cerebral infarction.Methods 208 patients with cerebral infarction were randomly selected as the research object,in which 96 patients receivd thrombolytic therapy,another 112 patients received conventional treatment.Results The scores of NIHSS thrombolytic group after treatment than in the conventional group decreased more obviously.Thrombolysis group before treatment and after treatment of the various stages of NIHSS score have significant difference（t=6.05,5.83,6.96,7.94,all P〈0.01）;thrombolytic therapy group and the conventional group after treatment of 90d after the Barthel index difference was statistically significant（t=4.67,P〈0.05）.Thrombolytic effect in treatment group is better than the conventional group,the difference was statistically significant（χ2=13.47,P〈0.05）. Conclusion Thrombolytic therapy can cerebral infarction affect of patients with influence,it can make the patient improved neurological function recovery,recover life skills,improve the quality of life.