超声心动图对肥厚型心肌病患者左室功能评价的临床研究

Clinical study on the left ventricular function in hypertrophic cardiomyopathy patients

目的 探讨超声心动图对肥厚型心肌病患者左室整体收缩及舒张功能的评估价值。方法 30例对照组和30例肥厚型心肌病患者分别应用常规超声测量左室舒张末内径（LVDd）、室间隔厚度（IVSd）、左室后壁厚度（LVPW）、左室射血分数（LVEF）及E/A。结果 肥厚型心肌病患者的室间隔厚度［（16.47±2.08）cm］、左室后壁厚度［（10.28±0.56）cm］及左室射血分数［（62.18±6.74）%］明显高于对照组［（9.56±0.45）cm、（9.30±0.48）cm、（57.66±5.22）%］（t=－17.809、－4.756、－2.911,均P〈0.05）,而左室舒张末内径［（40.28±3.86）cm］、E/A［（0.99±0.17）］较对照组降低［（45.15±3.84）cm、（1.10±0.24）］（t=4.899、2.132,均P〈0.05）。结论 超声心动图能很好的评价肥厚型心肌病患者左室整体收缩及舒张功能,有利于指导临床诊疗。

Objective To explore the left ventricular overall systolic and diastolic function in hypertrophic cardiomyopathy （HCM） patients with echocardiography.Methods 30 normal people and 30 hypertrophic cardiomyopathy patients were examined by routine echocardiography and examine the results of LVDd,IVSd,LVPW,LVFE and E/A.Results The results of IVSd [（16.47±2.08）cm],LVPW [（10.28±0.56）cm]and LVEF[（62.18±6.74）%] in HCM patients were superior than control group[（9.56±0.45）cm,（9.30±0.98）cm,（57.66±5.22）%]（t=-17.809,-4.756,-2.91,all P〈0.05） while the results of LVDd [（40.28±3.80）cm] and E/A [（0.99±0.17）] of HCM patients were obviously lower than control group [（45.15±3.84）cm,（1.10±0.24）] （t=4.899,2.132,all P〈0.05） and LVEF was obviously larger than control group（P〈0.05）. Conclusion Echocardiography can exactly evaluate left ventricular overall systolic and diastolic function in hypertrophic cardiomyopathy（HCM）patients and guide the diagnosis and treatment.