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TLR4与肿瘤放疗的研究进展 被引量:2

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摘要 Toll样受体4(Toll-like receptors 4,TLR4)是连接天然免疫与特异性免疫的重要模式识别受体(pattern recognition receptors,PRRs)。放射治疗通过促进TLR4内源性和外源性配体释放而激活炎性反应通路,而慢性炎症的产生又影响放疗效果,这是临床肿瘤放疗比较棘手的问题。本文通过对肿瘤放疗与TLR4介导的炎性反应通路间分子机制及作用原理的阐述,
作者 肖雯 徐海帆
出处 《现代医药卫生》 2013年第2期219-220,共2页 Journal of Modern Medicine & Health
基金 湖南省教育厅科学研究一般项目(06C706)
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