卡前列甲酯栓在剖宫产术中预防产后出血的临床观察

Intraoperative application card cesarean section front carboprost prevent postpartum hemorrhage of methyl clinical observation

目的:探讨卡前列甲酯栓在剖宫产术中预防产后出血的有效性和安全性。方法:剖宫产患者400例随机分为实验组200例和对照组200例,实验组在胎儿娩出后舌下含服卡前列甲酯栓1mg,两组在胎儿娩出后均向子宫肌层注入缩宫素20IU,观察两组术后2h及产后24h的出血量。结果:实验组产后2h及产后24h的出血量分别为152±13.6ml及216±18.3ml;对照组产后2h及产后24h的出血量分别为206±21.5ml及410±36.5ml。两组术后2h及产后24h的出血量比较,差异有统计学意义(P<0.05);实验组未出现明显副反应。结论:卡前列甲酯栓在剖宫产术中促进子宫收缩作用明显,能较好地预防产后出血,且舌下含服给药方便、安全。

Objective：To observe the effects of carboprost suppository on reduction of postpartum bleed- ing in cesarean section. Methods： Cesarean section 400 cases randomly points the experimental group 200 examples and the control group 200 examples. Methyl：carboprost suppository was given by sublingually in the study group af- ter delivery of fetus, meanwhile oxytocin was injected into the body of uterus. The amount of bleeding within 24 hours after delivery was measured. Results：The difference in the amount of bleeding between the two groups were significant（P〈0.05）. Conclusion： carboprost suppository is very effective in reduction of postpartum bleeding pa- tients underwent cesarean section.