江阴市2010年手足口病重症病例流行病学特征分析

Analysis on epidemiological characteristics of severe cases of hand-and-foot-mouth disease in 2010 in Jiangyin

目的了解辖区内手足口病(hand-foot-and-mouth disease,HFMD)重症病例的流行病学特征,为制定干预措施提供依据。方法对2010年所有手足口病重症病例进行流行病学个案调查,并对调查资料进行流行病学分析。结果 2010年江阴市手足口病报告发病1300例,发病率67.32/10万,重症40例,重症发生率3.08%,死亡1例,病死率为0.08%。乡镇重症病例报告病率差异有统计学意义(P<0.001)。辖区手足口病重症病例发病高峰为5～7月,年龄以5岁以下婴幼儿为主,病原以EV71感染为主。结论江阴市手足口病防控形势严峻,手足口病的发生有明显的年龄、季节和地区差异。对来自重点地区5岁以下年龄组手足口病患者应提高警惕,及早救治,加强健康教育宣传,同时加强手足口病监测工作和疾病负担调查工作。

Objective To understand the epidemiological characteristics of severe hand-foot-and-mouth disease（HFMD）,and provide basis for intervention measures.Method Investigate all severe cases of HFMD in 2010 and do epidemiological analysis on the survey datas.Results A tatal of 1 300 HFMD cases were reported with the incidence rate of 67.32/100 000.40 cases of severe were reported with the severe incidence rate of 3.08%.1 died and the case fatality rate was 0.08%.There were statistical significant differences of the report disease rate of severe HFMD cases among the counties（P0.001）.The peak of severe HFMD was from May to July,most of them were less than 5 years old,and the main pathogen was EV71 infection.Conclusions The prevention situation of HFMD was serious in Jiangyin.Incidence were different among ages,seasons and places.The children under 5 years old from key regions should be on the alert with early treatment and health education propaganda.At the same time,we should strengthen surveillance and disease burden research on HFMD.