小剂量茶碱口服联合小剂量糖皮质激素吸入治疗COPD的疗效观察被引量：2

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摘要目的:比较小剂量茶碱口服联合小剂量糖皮质激素吸入治疗慢性阻塞性肺疾病(COPD)的疗效。方法:将50例COPD患者均分为两组,每组25例。茶碱组口服缓释茶碱0.2g,2次/日,疗程6个月;联合组:口服缓释茶碱0.2g,2次/日,二丙酸倍氯米松(BDP)每天300μg吸入,疗程6个月。对照治疗前后患者的肺功能:第1秒用力呼气容积(FEV1)占预计值的百分比(%)、FEV1/用力肺活量(FVC)变化,比较治疗前后症状及生活质量评分;随访复发住院率以及药物不良反应。结果:治疗前后两组COPD患者肺功能FEV1占预计值%、FEV1/FVC均有不同程度的下降,但联合组下降速度小于茶碱组(P<0.05);生活质量评分两组均有改善,但联合组优于茶碱组(P<0.05);复发住院率及药物不良反应两组无明显变化(P>0.05)。结论:小剂量茶碱口服联合小剂量糖皮质激素吸入治疗COPD优于单用茶碱。

作者杨君明

机构地区四川广元市旺苍县静乐寺医院

出处《中国社区医师（医学专业）》 2013年第2期124-125,共2页

关键词茶碱糖皮质激素慢性阻塞性肺疾病

分类号 R511.6 [医药卫生—内科学]

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