无创正压通气治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭临床观察

Clinical observation of noninvasive positive pressure ventilation in the treatment of chronic obstructive pulmonary disease complicated with typeⅡrespiratory failure

目的观察无创正压通气(NPPV)治疗慢性阻塞性肺疾病(COPD)合并Ⅱ型呼吸衰竭的疗效。方法将58例慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者随机分为治疗组29例与对照组29例。对照组用吸氧、常规药物治疗,治疗组在吸氧、常规药物治疗的基础上加无创正压通气治疗。结果治疗组治疗前、后pH值、PaO2、PaCO2分别与对照组治疗前、后比较,治疗前差异无统计学意义(P>0.05),治疗后差异有统计学意义(P<0.05)。结论 NPPV对COPD合并Ⅱ型呼吸衰竭患者有较好的疗效,可以较快的缓解患者的临床症状,降低PaCO2值,提高PaO2值,值得推广使用。

Objective To observe the effects of noninvasive positive pressure ventilation（NPPV） on chronic obstructive pulmonary disease（COPD） complicated with typeⅡrespiratory failure.Methods Total 58 cases with chronic obstructive pulmonary disease complicated with type Ⅱrespiratory failure were evenly divided into the treatment group and the control group.Oxygenabsorption and routine therapy was given to the control group,noninvasive positive pressure ventilation was given to the treatment group on the basis of oxygenabsorption and routine therapy.Results The value of pH,PaO2 and PaCO2 before treatment in the treatment group compared with those in the control group,there was no statistical diference（P 0.05）.And the value of pH,PaO2 and PaCO2 after treatment in the treatment group compared with those in the control group,there was statistical diference（P 0.05）.Conclusion COPD patients complicated with typeⅡrespiratory failure can respond well to NPPV.By reduce PaCO2 value and improve PaO2 value,NPPV quickly relieved the patient＇s clinical symptoms and this treatment should be widely applied.