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妊娠期甲状腺功能减低症的筛查与转归 被引量:22

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摘要 目的探讨妊娠期甲状腺功能减退症(简称甲减)筛查的意义,观察妊娠期甲减患者的妊娠结局。方法测定301例妊娠妇女的血清促甲状腺激素(TSH)、甲状腺过氧化物酶抗体(TPOAb)、游离甲状腺素(FT4),比较甲减治疗组、甲减未治疗组与正常对照组间不同妊娠结局。结果甲减未治疗组的产科并发症、早产、流产的发生率较正常对照组高,自然顺产率较正常对照组低(P<0.05);甲减治疗组与正常对照组的妊娠结局、产科并发症发生率差异无统计学意义(P>0.05),而3组患者新生儿出生体重、身长及Apgar评分差异无统计学意义。结论妊娠期甲减的筛查具有重要意义,妊娠合并甲减患者如能及时足量甲状腺素替代治疗,能明显改善围产结局。
出处 《广东医学》 CAS CSCD 北大核心 2013年第1期119-121,共3页 Guangdong Medical Journal
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