缺血性脑卒中恢复早期气虚和阴虚阳亢证的变化与运动功能的关系

Relationship between Motor Function and TCM Syndromes in Early Recovery Stage after Ischemic Stroke

目的:探讨缺血性脑卒中恢复早期气虚和阴虚阳亢证的变化与运动功能的关系。方法:采集数据库中缺血性脑卒中患者在入组第1天和第21天的中医四诊信息,Fugl-Meyer运动功能量表的评分,改良。Ashworth痉挛评定量表的分级等数据,将所得数据进行差异性检验、相关分析等统计分析,观察缺血性脑卒中恢复早期气虚证和阴虚阳亢证的变化,探索其证候与肢体运动功能恢复进程的相关性。结果:入组第21天气虚证和阴虚阳亢证与运动功能的相关系数分别为-0.342(P<0.01)和-0.282(P<0.01),Ashworth分级与阴虚阳亢证的相关系数为0.262(P<0.05)。结论:缺血性脑卒中发病第二个时点运动功能与气虚证、阴虚阳亢证呈负相关,其中以分离运动最为显著,患肢的肌张力与阴虚阳亢证呈正相关。

Objective To investigate the relationship between motor function and qi deficiency syndrome,yin-asthenia and yang-hyperactivity syndrome in the early stages of ischemic stroke.Methods Using existing data from a data base,this research investigated a total of 62 ischemic stroke patients,to whom assessments were administered at baseline and at 3-week follow-up.The assessments included the Modified Ashworth Scale,Fugl-Meyer Assessment,and the Traditional Chinese Medicine(TCM) symptom score.Difference test,correlative test and regression analysis were performed to investigate the relationship between TCM syndrome and the process of motor recovery after ischemic stroke.Results The coefficients of correlation between motor function and qi deficiency syndrome,yin-asthenia and yang-hyperactivity syndrome are -0.342(P< 0.01) and -0.282(P< 0.01),respectively.The coefficient of correlation between Modified Ashworth Scale and yin-asthenia and yang-hyperactivity syndrome is 0.262(P < 0.05).Conclusions At 3-week follow-up,there is a significantly negative correlation between qi deficiency syndrome and motor function,and there is also a significantly negative correlation between yin-asthenia and yang-hyperactivity syndrome and motor function,especially with isolated movement.Muscular tone is positively correlated with yin-asthenia and yang-hyperactivity syndrome at 3-week follow-up.