摘要
目前,世界范围内肝硬化发病率保持在较高水平,对人类生命健康具有较大的威胁.在我国,病毒性肝炎是导致肝硬化的主要致病因素,尤其以乙型病毒性肝炎性肝硬化最常见.肝硬化腹水的形成是门静脉高压和肝功能减退共同作用的结果,而腹水的形成是肝硬化发展为肝功能失代偿期最突出的临床表现.对腹水形成机制的研究有助于指导临床更为准确的用药,以减轻患者的精神及经济压力.
Liver cirrhosis has a high morbidity and poses a large threat to human health worldwide. In China, viral hepatitis, especially hepatitis B, is the main pathogenic factor of liver cirrhosis. Ascites formation in cirrhosis is the result of combined action of portal hypertension and liver function impairment, and it is the most prominent clinical manifestation of decompensated cirrhosis. The understanding of pathophysiology of ascites formation can help provide more accurate treatment of this condition so as to alleviate patients' mental and economic burdens.
出处
《世界华人消化杂志》
CAS
北大核心
2013年第2期160-165,共6页
World Chinese Journal of Digestology
关键词
肝硬化
腹水
形成机制
Cirrhosis
Ascites
Pathophysiology